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International Journal of Phytomedicine and Phytotherapy

Table 1 Effects of XNE on relative organ weights of male and female rats at the end of the 90-day safety assessments

From: Safety assessment of the standardized aqueous extract from solid-state cultured Xylaria nigripes (Wuling Shen) in rats

 

Relative organ weight (%)a

Control

Low

Medium

High

Male

 Heart

0.31 ± 0.03

0.32 ± 0.04

0.32 ± 0.04

0.33 ± 0.02

 Liver

3.29 ± 0.42

3.19 ± 0.17

3.17 ± 0.20

3.17 ± 0.40

 Kidney

0.71 ± 0.06

0.68 ± 0.05

0.72 ± 0.05

0.75 ± 0.05

 Adrenal glands

0.012 ± 0.002

0.011 ± 0.002

0.011 ± 0.002

0.011 ± 0.001

 Testicles

0.60 ± 0.06

0.61 ± 0.06

0.58 ± 0.10

0.67 ± 0.04

 Brain

0.40 ± 0.04

0.39 ± 0.05

0.40 ± 0.05

0.44 ± 0.03

Female

 Heart

0.35 ± 0.03

0.34 ± 0.04

0.33 ± 0.04

0.36 ± 0.05

 Liver

3.22 ± 0.16

2.96 ± 0.36

2.83 ± 0.29

2.90 ± 0.35

 Kidney

0.78 ± 0.05

0.73 ± 0.07

1.01 ± 1.03

0.73 ± 0.08

 Adrenal glands

0.022 ± 0.004

0.022 ± 0.003

0.023 ± 0.003

0.023 ± 0.008

 Ovary

0.028 ± 0.004

0.030 ± 0.005

0.029 ± 0.003

0.035 ± 0.011

 Brain

0.70 ± 0.05

0.70 ± 0.08

0.68 ± 0.09

0.74 ± 0.08

  1. Key: Data are expressed as mean ± SD (n = 10)
  2. aRelative organ weight (%) = Organ weight / Body weight × 100