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International Journal of Phytomedicine and Phytotherapy

Table 1 Effects of XNE on relative organ weights of male and female rats at the end of the 90-day safety assessments

From: Safety assessment of the standardized aqueous extract from solid-state cultured Xylaria nigripes (Wuling Shen) in rats

  Relative organ weight (%)a
Control Low Medium High
Male
 Heart 0.31 ± 0.03 0.32 ± 0.04 0.32 ± 0.04 0.33 ± 0.02
 Liver 3.29 ± 0.42 3.19 ± 0.17 3.17 ± 0.20 3.17 ± 0.40
 Kidney 0.71 ± 0.06 0.68 ± 0.05 0.72 ± 0.05 0.75 ± 0.05
 Adrenal glands 0.012 ± 0.002 0.011 ± 0.002 0.011 ± 0.002 0.011 ± 0.001
 Testicles 0.60 ± 0.06 0.61 ± 0.06 0.58 ± 0.10 0.67 ± 0.04
 Brain 0.40 ± 0.04 0.39 ± 0.05 0.40 ± 0.05 0.44 ± 0.03
Female
 Heart 0.35 ± 0.03 0.34 ± 0.04 0.33 ± 0.04 0.36 ± 0.05
 Liver 3.22 ± 0.16 2.96 ± 0.36 2.83 ± 0.29 2.90 ± 0.35
 Kidney 0.78 ± 0.05 0.73 ± 0.07 1.01 ± 1.03 0.73 ± 0.08
 Adrenal glands 0.022 ± 0.004 0.022 ± 0.003 0.023 ± 0.003 0.023 ± 0.008
 Ovary 0.028 ± 0.004 0.030 ± 0.005 0.029 ± 0.003 0.035 ± 0.011
 Brain 0.70 ± 0.05 0.70 ± 0.08 0.68 ± 0.09 0.74 ± 0.08
  1. Key: Data are expressed as mean ± SD (n = 10)
  2. aRelative organ weight (%) = Organ weight / Body weight × 100