Hypoglycemic and antioxidative activities of ethanol seed extract of Hunteria umbellate (Hallier F.) on streptozotocin-induced diabetic rats

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of H. umbellata on oral glucose tolerance test in diabetic rats

GROUPS	Zero time	30 min	60 min	120 min	150 min
CONTROL	82.83 ± 6.60 ^b	151.83 ± 28.20 ^b	157.16 ± 12.05 ^b	116.16 ± 7.52 ^b	89.33 ± 6.40 ^b
60 mg/kg STZ	421.00 ± 42.43^*a	495.40 ± 64.06^*a	466.00 ± 76.24^*a	423.40 ± 85.60^*a	362.40 ± 78.97^*a
60 mg/kg STZ + METFORMIN	188.20 ± 64.38^b	159.20 ± 45.35^b	94.60 ± 26.78^b	74.60 ± 12.96 ^b	70.80 ± 11.55 ^b
60 mg/kg STZ + H.U. 400 mg	368.33 ± 95.86^*	450.33 ± 74.43^*a	393.00 ± 80.10^*a	330.00 ± 66.05^*a	247.16 ± 74.13^*a
60 mg/kg STZ + H.U. 800 mg	230.66 ± 90.93	474.00 ± 35.23^*a	450.66 ± 52.34^*a	408.66 ± 51.77^*a	353.00 ± 67.81^*a

Superscripts ^{* a b} represent values that are significantly (p < 0.05) different from negative control, metformin treated group and positive control respectively