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International Journal of Phytomedicine and Phytotherapy

Table 1 The most important pharmacological effects of galactomannan

From: Diosgenin and galactomannans, natural products in the pharmaceutical sciences

Health benefits Key points Reference
Antidiabetic activities a. Galactomannan may reduce the glycemic index of starch, and regulates postprandial blood glucose. [37]
Antioxidant activities a. Galactomannan I and II mainly include D-mannose and D-galactose which have shown antioxidant activities. [38, 39]
Anticancer activities a. Galactomannan from Sesbania cannabina has shown anticancer activity which is related to increase caspase-12 expression. [40]
Anticholinesterase activities a. Galactomanna II indicated strong anticholinesterase activity. [39]
Antiviral activities a. Sulfated galactomannans effectively prevented the infection of cells by viruses and the degree of substitution and molecular weights. [41]
Dengue virus a. Galactomannan extracted from Leucaena leucocephala seeds (GML), indicated that GML is a potential polysaccharide for biomaterials development which could involve interactions between Concanavalia ensiformis seeds (ConA) in immune system and viruses. [42]
Gastric diseases a. Galactomannans from Caesalpinia pulcherrima can be basis for new compounds in the treatment of gastric diseases. [43]