International Journal of Phytomedicine and Phytotherapy
Table 1 The most important pharmacological effects of galactomannan
From: Diosgenin and galactomannans, natural products in the pharmaceutical sciences
Health benefits | Key points | Reference |
|---|---|---|
Antidiabetic activities | a. Galactomannan may reduce the glycemic index of starch, and regulates postprandial blood glucose. | [37] |
Antioxidant activities | a. Galactomannan I and II mainly include D-mannose and D-galactose which have shown antioxidant activities. | |
Anticancer activities | a. Galactomannan from Sesbania cannabina has shown anticancer activity which is related to increase caspase-12 expression. | [40] |
Anticholinesterase activities | a. Galactomanna II indicated strong anticholinesterase activity. | [39] |
Antiviral activities | a. Sulfated galactomannans effectively prevented the infection of cells by viruses and the degree of substitution and molecular weights. | [41] |
Dengue virus | a. Galactomannan extracted from Leucaena leucocephala seeds (GML), indicated that GML is a potential polysaccharide for biomaterials development which could involve interactions between Concanavalia ensiformis seeds (ConA) in immune system and viruses. | [42] |
Gastric diseases | a. Galactomannans from Caesalpinia pulcherrima can be basis for new compounds in the treatment of gastric diseases. | [43] |