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International Journal of Phytomedicine and Phytotherapy

Table 3 Effect of crude extract and fractions of Gymnema sylvestre on Hematological Parameters in rats

From: Acute and sub-acute toxicity profile of crude extract and fractions of Gymnema sylvestre

Extract/Dose (mg/kg bodyweight)

Hb (g/dl)

PCV (%)

MCV (fl)

MCHC (g/dl)

RBC (×1012dl)

WBC (×109dl)

Normal

14.50 ± 0.50b

52.00 ± 1.00b

56.50 ± 1.50b

30.50 ± 0.50a

8.10 ± 0.60a

8.00 ± 1.00c

Ethylacetate 100

14.00 ± 2.00b

52.00 ± 4.00b

58.50 ± 0.50c

31.50 ± 2.50b

7.40 ± 0.10a

7.00 ± 0.50b

Ethylacetate 300

13.50 ± 0.50a

50.00 ± 1.00a

57.50 ± 0.50b

29.50 ± 0.50a

7.70 ± 0.10a

7.50 ± 0.50b

Ethylacetate 600

15.00 ± 2.00c

49.00 ± 1.00a

58.50 ± 0.50c

31.50 ± 1.50b

8.25 ± 0.35a

6.50 ± 0.50ab

N-hexane 100

14.50 ± 0.50b

52.00 ± 0.01b

57.50 ± 0.50b

31.00 ± 1.00b

8.00 ± 0.40a

7.00 ± 0.50b

N-hexane 300

14.00 ± 0.10b

50.50 ± 0.50a

57.50 ± 0.50b

31.50 ± 1.50b

7.30 ± 0.40a

7.50 ± 0.50b

N-hexane 600

15.00 ± 3.00c

50.00 ± 1.00a

56.50 ± 0.50a

30.50 ± 1.50a

7.90 ± 0.10a

5.50 ± 0.50a

Crude 100

14.50 ± 0.50b

51.50 ± 3.50b

57.50 ± 2.50b

31.00 ± 0.01b

8.20 ± 0.40a

7.50 ± 0.50b

Crude 300

14.50 ± 2.50b

49.50 ± 0.50a

58.50 ± 0.50c

31.50 ± 1.50b

7.55 ± 0.50a

7.00 ± 0.01b

Crude 600

13.50 ± 0.50a

52.50 ± 0.50b

58.50 ± 0.50c

31.50 ± 2.50b

7.90 ± 0.10a

5.50 ± 0.50a

  1. Data are Mean ± SEM of triplicate determinations. Mean with different superscripts alphabet differ significantly (p < 0.05). Key: Hb = hemoglobin, PCV = packed cell volume, MCV = mean cell volume, MCHC = mean cell hemoglobin concentration, RBC = red blood cells, WBC = white blood cells