Safety and influence of a novel extract of fenugreek on healthy young women: a randomized, double-blinded, placebo-controlled study

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 3 Hormone levels of placebo and FHE groups

Parameter	Placebo		FHE supplemented group		P-value
Parameter	Baseline	End of Study	Baseline	End of Study	P-value
Estradiol (pmol/L)	196.8 ± 55.4	207.1 ± 45.9	206.7 ± 58.4	240.3 ± 57.9^#	0.040
Progesterone (nmol/L)	2.47 ± 0.92	2.59 ± 0.82	2.61 ± 0.70	2.9 ± 0.58	0.174
Follicle stimulating hormone (IU/L)	13.86 ± 4.54	13.15 ± 4.47	14.36 ± 5.69	12.97 ± 5.89	0.879
Total testosterone (ng/dL)	30.02 ± 7.65	32.14 ± 7.79	31.94 ± 7.47	37.75 ± 9.29^#	0.012
Free testosterone (pg/dL)	28.25 ± 8.59	30.49 ± 8.72	29.11 ± 6.09	35.8 ± 6.7^#	0.025

Hormone levels of placebo and FHE groups at baseline vs end of study. A 2 × 2 repeated measures (RM) analysis of variance were performed with Bonferroni post hoc corrections. Values are expressed as Mean ± SD. ^# indicate baseline vs end of study at P ≤ 0.05