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International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of EEC on biochemical parameters administered orally for 12 consecutive days

From: Investigation of nootropic potential of ethanol extract of Elettaria cardamomum Maton fruit (Cardamom): a spice of India

Groups

n

Biochemical parameters (on 13th day)

AChE activity (U/g)

Cholesterol (mg/dl)

Glucose (U/g)

MDA (µmol/g of tissue)

GSH (µmol/g of tissue)

Control (Normal saline)

6

16.9 ± 1.09

114 ± 2.17

132.06 ± 4.98

0.240 ± 0.016

1.47 ± 0.10

Piracetam (400 mg/kg, i.p.)

6

10.41 ± 0.61**

81.33 ± 2.90**

106.89 ± 4.03**

0.99 ± 0.01**

2.09 ± 0.079**

EEC (100 mg/kg, p.o.)

6

14.90 ± 0.69

102.42 ± 1.54*

124.46 ± 4.89

0.201 ± 0.009

1.96 ± 0.09**

EEC (300 mg/kg, p.o.)

6

13.58 ± 0.58

96.5 ± 1.48**

119.89 ± 4.03

0.192 ± 0.01

1.98 ± 0.03**

EEC (500 mg/kg, p.o.)

6

11.90 ± 0.73**

89.0 ± 4.12**

117.26 ± 4.25

0.172 ± 0.02*

2.12 ± 0.01**

Diazepam (1 mg/kg, i.p.)

6

29.72 ± 0.88**

118.3 ± 3.79

142.05 ± 5.08

0.244 ± 0.025

1.17 ± 0.02*

  1. All values are mean ± SEM (n = number of animals in each group). Data was analyzed using one-way ANOVA followed by Dunnett test. *** p < 0.001, ** p < 0.01 and * p < 0.05 vs. normal control group
  2. EEC: ethanolic extract of Elettaria cardamomum; AChE: acetylcholinesterase; MDA: malondialdehyde; GSH: glutathione