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International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of EEC on biochemical parameters administered orally for 12 consecutive days

From: Investigation of nootropic potential of ethanol extract of Elettaria cardamomum Maton fruit (Cardamom): a spice of India

Groups n Biochemical parameters (on 13th day)
AChE activity (U/g) Cholesterol (mg/dl) Glucose (U/g) MDA (µmol/g of tissue) GSH (µmol/g of tissue)
Control (Normal saline) 6 16.9 ± 1.09 114 ± 2.17 132.06 ± 4.98 0.240 ± 0.016 1.47 ± 0.10
Piracetam (400 mg/kg, i.p.) 6 10.41 ± 0.61** 81.33 ± 2.90** 106.89 ± 4.03** 0.99 ± 0.01** 2.09 ± 0.079**
EEC (100 mg/kg, p.o.) 6 14.90 ± 0.69 102.42 ± 1.54* 124.46 ± 4.89 0.201 ± 0.009 1.96 ± 0.09**
EEC (300 mg/kg, p.o.) 6 13.58 ± 0.58 96.5 ± 1.48** 119.89 ± 4.03 0.192 ± 0.01 1.98 ± 0.03**
EEC (500 mg/kg, p.o.) 6 11.90 ± 0.73** 89.0 ± 4.12** 117.26 ± 4.25 0.172 ± 0.02* 2.12 ± 0.01**
Diazepam (1 mg/kg, i.p.) 6 29.72 ± 0.88** 118.3 ± 3.79 142.05 ± 5.08 0.244 ± 0.025 1.17 ± 0.02*
  1. All values are mean ± SEM (n = number of animals in each group). Data was analyzed using one-way ANOVA followed by Dunnett test. *** p < 0.001, ** p < 0.01 and * p < 0.05 vs. normal control group
  2. EEC: ethanolic extract of Elettaria cardamomum; AChE: acetylcholinesterase; MDA: malondialdehyde; GSH: glutathione