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International Journal of Phytomedicine and Phytotherapy

Table 10 Effect of S. caseolaris fruits on SGPT, SGOT, total Cholesterol, triglyceride, creatinine, urea and bilirubin in STZ-induced diabetic mice

From: Toxicological screening and evaluation of anti-allergic and anti-hyperglycemic potential of Sonneratia caseolaris (L.) Engl. fruits

Group Control (2 % tween, 0.5 mL/ mice) Diabetic Control (2 % tween, 0.5 mL/ mice) Standard (Glibenclamide 10 mg/kg) Test-I (EESC, 300 mg/kg) Test-II (EESC, 500 mg/kg)
SGPT (U/L) 42.84 ± 5.71 81.84 ± 5.23# 45.17 ± 4.94** 69.33 ± 3.75 55.50 ± 5.24*
SGOT (U/L) 45.84 ± 6.07 110.84 ± 6.32# 51.67 ± 4.15** 93.67 ± 3.25* 56.33 ± 5.57**
Cholesterol (mg/dL) 119.0 ± 5.32 183.50 ± 8.28# 111.50 ± 3.88** 177.33 ± 5.43 131.27 ± 7.89*
Triglyceride (mg/dL) 95.00 ± 6.73 172.83 ± 8.43# 93.12 ± 4.71** 168.50 ± 4.02 125.83 ± 8.21*
Creatinine (mg/dL) 0.63 ± 0.027 3.25 ± 0.14# 0.96 ± 0.07* 1.44 ± 0.08* 1.20 ± 0.05*
Urea (mg/dL) 29.00 ± 2.89 98.00 ± 2.67# 34.00 ± 2.41* 47.67 ± 1.78* 36.67 ± 2.32*
Bilirubin (mg/dL) 0.43 ± 0.02 2.60 ± 0.06# 0.61 ± 0.03* 1.12 ± 0.06* 0.93 ± 0.03*
  1. Values are expressed as mean ± standard error of mean (n = 6)
  2. # Indicates p < 0.0001 compared with control
  3. * Indicates p ˂ 0.05 compare with STZ control
  4. ** Indicates p ˂ 0.0001 compare with diabetic control