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International Journal of Phytomedicine and Phytotherapy

Table 10 Effect of S. caseolaris fruits on SGPT, SGOT, total Cholesterol, triglyceride, creatinine, urea and bilirubin in STZ-induced diabetic mice

From: Toxicological screening and evaluation of anti-allergic and anti-hyperglycemic potential of Sonneratia caseolaris (L.) Engl. fruits

Group

Control (2 % tween, 0.5 mL/ mice)

Diabetic Control (2 % tween, 0.5 mL/ mice)

Standard (Glibenclamide 10 mg/kg)

Test-I (EESC, 300 mg/kg)

Test-II (EESC, 500 mg/kg)

SGPT (U/L)

42.84 ± 5.71

81.84 ± 5.23#

45.17 ± 4.94**

69.33 ± 3.75

55.50 ± 5.24*

SGOT (U/L)

45.84 ± 6.07

110.84 ± 6.32#

51.67 ± 4.15**

93.67 ± 3.25*

56.33 ± 5.57**

Cholesterol (mg/dL)

119.0 ± 5.32

183.50 ± 8.28#

111.50 ± 3.88**

177.33 ± 5.43

131.27 ± 7.89*

Triglyceride (mg/dL)

95.00 ± 6.73

172.83 ± 8.43#

93.12 ± 4.71**

168.50 ± 4.02

125.83 ± 8.21*

Creatinine (mg/dL)

0.63 ± 0.027

3.25 ± 0.14#

0.96 ± 0.07*

1.44 ± 0.08*

1.20 ± 0.05*

Urea (mg/dL)

29.00 ± 2.89

98.00 ± 2.67#

34.00 ± 2.41*

47.67 ± 1.78*

36.67 ± 2.32*

Bilirubin (mg/dL)

0.43 ± 0.02

2.60 ± 0.06#

0.61 ± 0.03*

1.12 ± 0.06*

0.93 ± 0.03*

  1. Values are expressed as mean ± standard error of mean (n = 6)
  2. # Indicates p < 0.0001 compared with control
  3. * Indicates p Ë‚ 0.05 compare with STZ control
  4. ** Indicates p Ë‚ 0.0001 compare with diabetic control