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Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 5 Assessment of allergy-like symptoms in mice

From: Toxicological screening and evaluation of anti-allergic and anti-hyperglycemic potential of Sonneratia caseolaris (L.) Engl. fruits

Group

No. of sneezing

No. of Scratching

Nasal score

Negative Control (ethyl acetate only)

2.33 ± 1.86

19.33 ± 6.69

0

Positive control (5 % TDI treated)

31.00 ± 2.78#

161.33 ± 6.73#

3.0 ± 0.00

Standard (Cetirizine, 20 mg/kg)

13.75 ± 1.49*

63.0 ± 9.93*

0.4 ± 0.24*

Test-I (EESC, 300 mg/kg)

26.43 ± 2.59*

126.71 ± 14.03*

1.2 ± 0.2*

Test-II (EESC, 500 mg/kg)

20.33 ± 2.64*

96.5 ± 10.74*

0.4 ± 0.24*

  1. Values are expressed as mean ± standard error of mean (n = 6)
  2. EESC Ethanolic extract of S. caseolaris (L.) Engl
  3. # indicates p<0.05 vs. negative control and *indicates p<0.05 vs. Positive control
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