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International Journal of Phytomedicine and Phytotherapy

Table 1 Effect of A. spinosus on biochemical parameters in male rats

From: Toxicological evaluation of the dried hydroethanolic extract of Amaranthus spinosus L. roots in Artemia salina larvae and Sprague Dawley rats

Parameters

Control

A. spinosus

500 mg/kg/day

A. spinosus

1000 mg/kg/day

Urea (g/L)

0.369 ±0.041

0.338 ± 0.028

0.285 ± 0.044

Creatinine (mg/L)

6.762 ± 0.312

7.600 ± 0.303

7.320 ± 0.188

CPK (IU/L)

593.512 ± 53.677

535.358 ± 24.850

456.034 ± 58.569

ASAT (IU/L)

176.060 ± 8.968

159.600 ± 4.434

163.800 ± 6.248

ALAT (IU/L)

60.909 ± 4.186

60.200 ± 4.212

53.600 ± 5.344

ɣ-GT (IU/L)

7.100 ± 0.400

7.600 ± 0.678

8.200 ± 0.374

TG (g/L)

0.600 ± 0.079

0.572 ± 0.036

0.662 ± 0.055

TC (g/L)

0.683 ± 0.042

0.772 ± 0.028

0.726 ± 0.056

HDL-C (g/L)

0.379 ± 0.078

0.542 ± 0.032

0.470 ± 0.057

LDL-C (g/L)

0.207 ± 0.062

0.142 ± 0.015

0.150 ± 0.034

  1. CPK = creatinine phosphokinase; ASAT = aspartate aminotransferase; ALAT = alanine aminotransferase; ɣ-GT = ɣ-glutamyltranspeptidase; TG = triglycerides; Total-C = total cholesterol; HDL and LDL-C = high and Low-density lipoprotein cholesterol. The values were analysed with 1-way ANOVA and expressed as the mean ± SEM, then compared to the control. n = 5