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International Journal of Phytomedicine and Phytotherapy

Table 4 Effect of A. spinosus root extract in hematological parameters in female rats

From: Toxicological evaluation of the dried hydroethanolic extract of Amaranthus spinosus L. roots in Artemia salina larvae and Sprague Dawley rats

Parameters

Control

A. spinosus

500 mg/kg/day

A. spinosus

1000 mg/kg/day

RBC (106/µL)

61.70 ± 0.169

5.894 ± 0.109

6.090 ± 0.093

HGB (g/dL)

13.080 ± 0.280

12.440 ± 0.406

12.940 ± 0.340

HCT (%)

34.720 ± 0.878

32.780 ± 1.058

34.340 ± 1.375

MCV (fl.)

55.420 ± 0.828

55.520 ± 0.822

56.340 ± 1.451

MCH (pg)

20.900 ± 0.217

21.080 ± 0.340

21.240 ± 0.256

MCHC (g/dL)

37.740 ± 0.194

37.980 ± 0.547

37.780 ± 0.653

PLT (103/µL)

877.000 ± 120.557

916.200 ± 128.117

932.600 ± 65.472

WBC (103/µL)

4.000 ± 0.661

3.700 ± 0.633

3.160 ± 0.771

Neutrophils (%)

31.400 ± 6.250

33.200 ± 3.992

36.200 ± 5.826

Eosinophils (%)

1.800 ± 0.490

2.600 ± 0.510

3.000 ± 0.447

Basophils (%)

0.000 ± 0.000

0.000 ± 0.000

0.000 ± 0.000

Lymphocytes (%)

62.400 ± 7.089

59.600 ± 3.881

55.400 ± 5.715

Monocytes (%)

4.400 ± 1.691

4.600 ± 0.678

5.400 ± 0.510

RBC = red blood cells; HGB = hemoglobin; HCT = hematocrit; MCV = mean corpuscular volume; MCH = mean corpuscular hemoglobin; MCHC = mean corpuscular hemoglobin concentration; PLT = platelets; WBC = white blood cells. The values were analysed with 1-ways ANOVA and expressed as the mean ± SEM, then compared to the control. n = 5.