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International Journal of Phytomedicine and Phytotherapy

Table 3 Biochemical Profile for GC-500 compared to the control treatment

From: A formulation of Clausena anisata (Willd.) Hook. f. Ex Benth and Cassia sieberiana DC. alleviates the symptoms associated with osteoarthritis: a single-blind, randomised controlled trial of a traditional Ghanaian remedy

Parameter

GC-500

Control

CI

Baseline

End of Study

Baseline

End of Study

AST (IU/L)

23.34 (1.47)

22.70 (1.21)

26.54 (3.08)

24.0 (2.67)

−6.51 to 3.33

ALT (IU/L)

25.98 (1.25)

25.23 (1.47)

25.51 (1.65)

24.82 (1.93)

−3.90 to 5.26

ALP (IU/L)

124.9 (5.74)

123.8 (5.13)

125.9 (7.72)

122.1 (5.56)

−12.59 to 14.63

GGT (IU/L)

18.07 (1.32)

18.29 (0.98)

20.13 (1.21)

19.50 (1.44)

−4.81 to 3.81

LDH (IU/L)

55.87 (2.02)

54.71 (1.97)

54.84 (1.33)

54.60 (0.98)

−5.78 to 6.10

TPROT(g/dl)

6.89 (0.17)

6.93 (0.13)

7.20 (0.14)

7.04 (0.12)

−0.61 to 0.35

ALB (g/dl)

3.77 (0.13)

3.96 (0.12)

3.94 (0.25)

3.62 (0.24)

−0.34 to 0.60

TBIL (μmol/dl)

10.81 (0.89)

10.33 (0.80)

11.30 (0.61)

10.08 (0.35)

−3.17 to 2.23

Na+ (mmol/l)

138.1 (0.61)

137.9 (0.77)

138.9 (1.12)

137.0 (1.11)

−2.33 to 2.97

K+ (mmol/l)

4.14 (0.15)

4.05 (0.14)

4.10 (0.16)

3.88 (0.21)

−0.62 to 0.44

Cl (mmol/l)

99.29 (0.32)

98.78 (0.33)

99.20 (0.19)

98.62 (0.40)

−0.83 to 1.15

Urea (mmol/l)

3.62 (0.19)

3.14 (0.23)

3.90 (0.11)

3.84 (0.14)

−1.18 to .116

Creatinine (mmol/l)

79.06 (3.28)

75.62 (2.44)

78.73 (2.76)

76.71 (3.05)

−7.11 to 10.22

  1. Data is presented as Mean (±SD); N = 57: GC-500 (n = 44) & Control (n = 13)
  2. AST Aspartate transaminase, ALT Alanine aminotransferase, ALP Alkaline phosphatase, GGT γ-glutamyl transaminase, Na + Sodium, K + Potassium, Cl Chloride, LDH Lactate dehydrogenase, TBIL Total bilirubin, TPROT Total protein and ALB Albumin