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International Journal of Phytomedicine and Phytotherapy

Table 1 Effects of 21-days treatment of wound with PEG, Ag-NPs and Ag-INPs on haematological parameters of albino rats

From: Safety assessment of bio-synthesized iodine-doped silver nanoparticle wound ointment in experimental rats

Parameters

Control

Standard

Untreated

PEG

Ag NP

Ag-I NP

Hb (g/L)

10.95 ± 1.35bc

9.50 ± 0.00b

11.75 ± 1.05bc

13.35 ± 0.05c

13.50 ± 0.60c

4.95 ± 0.55a

PCV (%)

35.00 ± 3.00bc

30.00 ± 0.00b

37.00 ± 3.00bc

42.00 ± 2.00c

41.50 ± 1.50c

14.50 ± 1.50a

MCV (fL)

56.00 ± 2.00a

54.00 ± 1.00a

56.00 ± 2.00a

54.50 ± 2.50a

51.00 ± 0.00a

54.00 ± 0.00a

MCH (Pg)

15.50 ± 0.50b

17.00 ± 1.00b

16.00 ± 0.00b

17.00 ± 0.00b

13.00 ± 3.00ab

8.00 ± 2.00a

MCHC(g/dL)

28.00 ± 2.00b

31.00 ± 1.00b

30.00 ± 0.00b

31.50 ± 1.50b

26.00 ± 6.00b

13.50 ± 3.50a

RBC (× 1012/L)

7.25 ± 1.25ab

5.60 ± 0.30a

7.35 ± 0.55ab

7.75 ± 0.05ab

11.05 ± 1.95b

7.15 ± 2.45ab

PLC(× 109/L)

6.98 ± 0.00a

5.35 ± 0.00a

7.23 ± 0.00a

8.23 ± 6.50a

7.64 ± 3.40a

1.27 ± 9.28a

TWBC(× 109/L)

3.10 ± 0.00ab

5.25 ± 0.25bc

5.10 ± 1.10bc

5.60 ± 0.60c

10.20 ± 0.90d

2.65 ± 0.55a

Neu (%)

9.00 ± 1.00a

8.50 ± 0.50a

7.50 ± 0.50a

10.50 ± 0.50a

10.50 ± 3.50a

17.50 ± 12.50a

Lym (%)

75.00 ± 1.00a

72.00 ± 3.00a

70.50 ± 2.50a

75.50 ± 4.50a

80.50 ± 3.50a

52.00 ± 18.00a

MEB (%)

16.00 ± 2.00ab

19.50 ± 3.50ab

22.00 ± 2.00ab

14.00 ± 4.00a

9.00 ± 7.00a

30.50 ± 5.50b

RDWC (%)

15.30 ± 0.40a

15.85 ± 0.55a

16.15 ± 0.25ab

15.55 ± 0.85a

18.90 ± 0.60c

18.75 ± 1.35bc

  1. Biochemical analysis Values are expressed in mean ± standard error of mean. Values with the same superscript across the row have no significant different at p < 0.05
  2. Hb Haemoglobin count, PCV packed cell volume, MCV mean cell volume, MCH Mean corpuscular haemoglobin, MCHC Mean corpuscular haemoglobin concentration, RBC red blood cells, PLCx102 platelet count, TWBC total white blood cells, Neu neutrophils, Lym lymphocytes, MEB monocytes, eosinophils, basophils and RDWC red cell distribution width