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International Journal of Phytomedicine and Phytotherapy

Table 1 Effects of 21-days treatment of wound with PEG, Ag-NPs and Ag-INPs on haematological parameters of albino rats

From: Safety assessment of bio-synthesized iodine-doped silver nanoparticle wound ointment in experimental rats

Parameters Control Standard Untreated PEG Ag NP Ag-I NP
Hb (g/L) 10.95 ± 1.35bc 9.50 ± 0.00b 11.75 ± 1.05bc 13.35 ± 0.05c 13.50 ± 0.60c 4.95 ± 0.55a
PCV (%) 35.00 ± 3.00bc 30.00 ± 0.00b 37.00 ± 3.00bc 42.00 ± 2.00c 41.50 ± 1.50c 14.50 ± 1.50a
MCV (fL) 56.00 ± 2.00a 54.00 ± 1.00a 56.00 ± 2.00a 54.50 ± 2.50a 51.00 ± 0.00a 54.00 ± 0.00a
MCH (Pg) 15.50 ± 0.50b 17.00 ± 1.00b 16.00 ± 0.00b 17.00 ± 0.00b 13.00 ± 3.00ab 8.00 ± 2.00a
MCHC(g/dL) 28.00 ± 2.00b 31.00 ± 1.00b 30.00 ± 0.00b 31.50 ± 1.50b 26.00 ± 6.00b 13.50 ± 3.50a
RBC (× 1012/L) 7.25 ± 1.25ab 5.60 ± 0.30a 7.35 ± 0.55ab 7.75 ± 0.05ab 11.05 ± 1.95b 7.15 ± 2.45ab
PLC(× 109/L) 6.98 ± 0.00a 5.35 ± 0.00a 7.23 ± 0.00a 8.23 ± 6.50a 7.64 ± 3.40a 1.27 ± 9.28a
TWBC(× 109/L) 3.10 ± 0.00ab 5.25 ± 0.25bc 5.10 ± 1.10bc 5.60 ± 0.60c 10.20 ± 0.90d 2.65 ± 0.55a
Neu (%) 9.00 ± 1.00a 8.50 ± 0.50a 7.50 ± 0.50a 10.50 ± 0.50a 10.50 ± 3.50a 17.50 ± 12.50a
Lym (%) 75.00 ± 1.00a 72.00 ± 3.00a 70.50 ± 2.50a 75.50 ± 4.50a 80.50 ± 3.50a 52.00 ± 18.00a
MEB (%) 16.00 ± 2.00ab 19.50 ± 3.50ab 22.00 ± 2.00ab 14.00 ± 4.00a 9.00 ± 7.00a 30.50 ± 5.50b
RDWC (%) 15.30 ± 0.40a 15.85 ± 0.55a 16.15 ± 0.25ab 15.55 ± 0.85a 18.90 ± 0.60c 18.75 ± 1.35bc
  1. Biochemical analysis Values are expressed in mean ± standard error of mean. Values with the same superscript across the row have no significant different at p < 0.05
  2. Hb Haemoglobin count, PCV packed cell volume, MCV mean cell volume, MCH Mean corpuscular haemoglobin, MCHC Mean corpuscular haemoglobin concentration, RBC red blood cells, PLCx102 platelet count, TWBC total white blood cells, Neu neutrophils, Lym lymphocytes, MEB monocytes, eosinophils, basophils and RDWC red cell distribution width