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International Journal of Phytomedicine and Phytotherapy

Table 5 Effect of the EESAL on the liver function parameters in Plasmodium berghei-infected mice

From: Sida acuta Burm.f. leaves ethanol extract ameliorates haematological and biochemical alterations induced by Plasmodium berghei ANKA-65 in mice

Groups Liver function markers
ALT (IU/L) ALP (IU/L) AST (IU/L) T. bil (mg/dl)
Normal control 20.25 ± 2.63a 64.50 ± 3.42a 37.00 ± 2.58a 0.45 ± 0.12b
Negative control 36.50 ± 3.42c 95.25 ± 6.70b 73.25 ± 10.63b 0.65 ± 0.08c
MP + 140 mg/kg b.w. of Artemether 25.50 ± 1.91b 62.25 ± 4.35a 41.25 ± 0.96a 0.52 ± 0.06b
MP + 200 mg/kg b.w. EESAL 20.50 ± 1.73a 67.25 ± 4.35a 36.75 ± 2.99a 0.41 ± 0.08ab
MP + 400 mg/kg b.w. EESAL 26.25 ± 2.63b 64.75 ± 3.50a 34.50 ± 3.11a 0.44 ± 0.02ab
MP + 600 mg/kg b.w. EESAL 20.00 ± 3.74a 62.25 ± 2.63a 35.25 ± 2.50a 0.37 ± 0.06a
  1. Results are expressed in Means ± SD (n = 6); At p < 0.05, mean values with different letters of the alphabets (a, b, c, d …) as superscripts in a column are statically different while mean values with similar alphabets are not statistically different
  2. AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, T. bil total bilirubin