Skip to main content

International Journal of Phytomedicine and Phytotherapy

Table 5 Effect of the EESAL on the liver function parameters in Plasmodium berghei-infected mice

From: Sida acuta Burm.f. leaves ethanol extract ameliorates haematological and biochemical alterations induced by Plasmodium berghei ANKA-65 in mice

Groups

Liver function markers

ALT (IU/L)

ALP (IU/L)

AST (IU/L)

T. bil (mg/dl)

Normal control

20.25 ± 2.63a

64.50 ± 3.42a

37.00 ± 2.58a

0.45 ± 0.12b

Negative control

36.50 ± 3.42c

95.25 ± 6.70b

73.25 ± 10.63b

0.65 ± 0.08c

MP + 140 mg/kg b.w. of Artemether

25.50 ± 1.91b

62.25 ± 4.35a

41.25 ± 0.96a

0.52 ± 0.06b

MP + 200 mg/kg b.w. EESAL

20.50 ± 1.73a

67.25 ± 4.35a

36.75 ± 2.99a

0.41 ± 0.08ab

MP + 400 mg/kg b.w. EESAL

26.25 ± 2.63b

64.75 ± 3.50a

34.50 ± 3.11a

0.44 ± 0.02ab

MP + 600 mg/kg b.w. EESAL

20.00 ± 3.74a

62.25 ± 2.63a

35.25 ± 2.50a

0.37 ± 0.06a

  1. Results are expressed in Means ± SD (n = 6); At p < 0.05, mean values with different letters of the alphabets (a, b, c, d …) as superscripts in a column are statically different while mean values with similar alphabets are not statistically different
  2. AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, T. bil total bilirubin