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International Journal of Phytomedicine and Phytotherapy

Table 6 Effect of the EESAL on lipid peroxidation and antioxidant parameters of Plasmodium berghei-infected mice

From: Sida acuta Burm.f. leaves ethanol extract ameliorates haematological and biochemical alterations induced by Plasmodium berghei ANKA-65 in mice

Groups

Lipid peroxidation and antioxidant parameters

MDA Conc. (mg/dl)

SOD activity (IU/L)

CAT activity (IU/L)

GSH Conc. (mg/dl)

Normal control

2.68 ± 0.99b

9.63 ± 0.42b

0.65 ± 0.02b

0.21 ± 0.05a

Malaria control

6.05 ± 0.68c

4.18 ± 0.38a

0.16 ± 0.05c

0.10 ± 0.01b

MP + 140 mg/kg b.w. of Artemether

2.25 ± 0.70ab

9.52 ± 0.74b

0.66 ± 0.06b

0.26 ± 0.07a

MP + 200 mg/kg b.w. EESAL

2.31 ± 0.39ab

9.94 ± 0.58b

0.68 ± 0.18b

0.22 ± 0.14a

MP + 400 mg/kg b.w. EESAL

2.28 ± 0.30ab

9.95 ± 0.39b

0.72 ± 0.10b

0.24 ± 0.05a

MP + 600 mg/kg b.w. EESAL

1.54 ± 0.59a

10.19 ± 0.19b

0.68 ± 0.06b

0.25 ± 0.03a

  1. Results are expressed in Means ± SD (n = 6); At p < 0.05, mean values with different letters of the alphabets (a, b, c, d …) as superscripts in a column are statically different while mean values with similar alphabets are not statistically different
  2. MDA malondialdehyde, SOD Superoxide dismutase, CAT catalase, GSH reduced glutathione