Table 6 Liver damage biomarkers of male Wistar rats administered with lead acetate and treated with methanol and methanol/acetone phenolic-rich extracts of N. latifolia fruit

Control (2 mL/kg bw. Normal Saline)

13.00 ± 1.73 ^a

7.60 ± 0.29 ^a

8.00 ± 0.23 ^a

0.65 ± 0.26 ^a

3.75 ± 0.32 ^f

2.60 ± 0.30 ^d

Silymarin (100 mg/kg bw.)

17.30 ± 3.56 ^d

12.03 ± 8.31^e

11.25 ± 5.62 ^c

1.17 ± 0.03 ^d

3.25 ± 0.87 ^e

2.20 ± 0.20 ^b

Untreated (2 mL/kg bw. Normal Saline)

47.50 ± 4.33 ^c

22.70 ± 0.46 ^f

27.50 ± 0.29 ^e

4.45 ± 0.38 ^g

1.45 ± 0.20 ^a

1.25 ± 0.32 ^a

150 mg/kg bw. MPR NLF

18.20 ± 0.12 ^d

9.30 ± 0.03 ^bc

12.00 ± 0.00 ^d

1.53 ± 1.10 ^f

2.90 ± 0.29 ^d

2.25 ± 0.14 ^b

300 mg/kg bw. MPR NLF

15.65 ± 0.38 ^c

8.10 ± 0.58 ^d

10.03 ± 1.15 ^b

1.10 ± 0.06 ^c

2.20 ± 0.90 ^c

2.10 ± 0.00 ^b

150 mg/kg bw. MAPR NLF

17.05 ± 0.23 ^d

10.05 ± 0.03^e

12.00 ± 0.04 ^c

1.33 ± 1.10 ^e

2.40 ± 0.29 ^c

2.20 ± 0.10 ^b

300 mg/kg bw. MAPR NLF

13.25 ± 0.38^a

9.20 ± 0.58 ^b

9.50 ± 1.15 ^b

0.80 ± 0.08 ^b

2.15 ± 0.90 ^b

2.40 ± 0.00 ^c