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International Journal of Phytomedicine and Phytotherapy

Table 6 Liver damage biomarkers of male Wistar rats administered with lead acetate and treated with methanol and methanol/acetone phenolic-rich extracts of N. latifolia fruit

From: Phenolic rich-extracts from Nauclea latifolia fruit restored Lead acetate-induced liver and kidney damaged in Wistar rats

Treatment ALP (U/L) AST (U/L) ALT (U/L) Conj. Bilirubin (mg/dL) Total Protein
(g/dL)
Albumin
(g/dL)
Control (2 mL/kg bw. Normal Saline) 13.00 ± 1.73 a 7.60 ± 0.29 a 8.00 ± 0.23 a 0.65 ± 0.26 a 3.75 ± 0.32 f 2.60 ± 0.30 d
Silymarin (100 mg/kg bw.) 17.30 ± 3.56 d 12.03 ± 8.31e 11.25 ± 5.62 c 1.17 ± 0.03 d 3.25 ± 0.87 e 2.20 ± 0.20 b
Untreated (2 mL/kg bw. Normal Saline) 47.50 ± 4.33 c 22.70 ± 0.46 f 27.50 ± 0.29 e 4.45 ± 0.38 g 1.45 ± 0.20 a 1.25 ± 0.32 a
150 mg/kg bw. MPR NLF 18.20 ± 0.12 d 9.30 ± 0.03 bc 12.00 ± 0.00 d 1.53 ± 1.10 f 2.90 ± 0.29 d 2.25 ± 0.14 b
300 mg/kg bw. MPR NLF 15.65 ± 0.38 c 8.10 ± 0.58 d 10.03 ± 1.15 b 1.10 ± 0.06 c 2.20 ± 0.90 c 2.10 ± 0.00 b
150 mg/kg bw. MAPR NLF 17.05 ± 0.23 d 10.05 ± 0.03e 12.00 ± 0.04 c 1.33 ± 1.10 e 2.40 ± 0.29 c 2.20 ± 0.10 b
300 mg/kg bw. MAPR NLF 13.25 ± 0.38a 9.20 ± 0.58 b 9.50 ± 1.15 b 0.80 ± 0.08 b 2.15 ± 0.90 b 2.40 ± 0.00 c