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International Journal of Phytomedicine and Phytotherapy

Table 7 Kidney damage biomarkers of male Wistar rats administered with lead acetate and treated with methanol and methanol/acetone phenolic-rich extracts of N. latifolia fruit

From: Phenolic rich-extracts from Nauclea latifolia fruit restored Lead acetate-induced liver and kidney damaged in Wistar rats

Treatment UREA (mg/dL) Na+ (mmol/L) K (mmol/L) Cl (mmol/L) Creatinine (mg/dL)
Control (2 mL/kg bw. Normal Saline) 32.50 ± 1.44 a 86.00 ± 0.58 a 3.75 ± 0.08 a 65.30 ± 3.17 a 0.60 ± 0.23 a
Silymarin (100 mg/kg bw.) 49.00 ± 5.19 c 100.50 ± 0.86 d 5.40 ± 0.06 d 72.00 ± 1.15 c 1.10 ± 0.11 e
Untreated (2 mL/kg bw. Normal Saline) 98.00 ± 5.70 f 136.50 ± 5.70 f 15.1 ± 0.23 e 99.50 ± 0.29 e 4.00 ± 0.00 f
150 mg/kg bw. MPR NLF 64.30 ± 1.59 e 110.41 ± 1.43 e 5.50 ± 1.57 d 80.00 ± 2.15 d 1.40 ± 0.11 b
300 mg/kg bw. MPR NLF 54.04 ± 3.46 d 98.50 ± 0.43 b 4.15 ± 0.15 b 74.50 ± 0.15 c 0.85 ± 0.85 c
150 mg/kg bw. MAPR NLF 52.00 ± 2.59 d 104.50 ± 2.59 d 4.70 ± 0.57 c 68.00 ± 1.15 b 1.15 ± 0.06 d
300 mg/kg bw. MAPR NLF 33.00 ± 0.57 b 93.50 ± 11.25 c 4.05 ± 1.15 b 65.00 ± 1.15 a 0.75 ± 0.14 b