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International Journal of Phytomedicine and Phytotherapy

Table 4 Summary of the study items and the results

From: Differential expression of gluconeogenic enzymes in early- and late-stage diabetes: the effect of Citrullus colocynthis (L.) Schrad. Seed extract on hyperglycemia and hyperlipidemia in Wistar-Albino rats model

Measured parameters

ET2D

LT2D

Before CCAE

After CCAE

Before CCAE

After CCAE

CCAE effect on short-term blood sugar (IPGTT)

↑↑

Extent of impaired glucose tolerance (AUC in IPGTT)

NA

↑↑

NA

Measured parameters on day 28

 FBS

↑↑

↓↓

 HbA1c

–e

 Hepatic PCC

 G6Pase mRNA

 PEPCK mRNA

 CPT1

↑↑

↓↓

 Hepatic TG

 Blood TG

 Body weight

 C-peptide

↓↓

 SREBP-1c mRNA

↓↓

 ACC mRNA

↓↓

 FAS mRNA

 PPARα mRNA

↑↑