Plate 3

Photomicrograph Sections of the Pancreatic Cells of Streptozotocin induced Diabetic Rats fed on a High Fat Diet. A = Glibenclamide (10 mg/kg): Reveals features of some acinar cells with islet-cells showing mildly dispersed pyknotic nuclei (long arrow) and mild dispersed lymphocytic infiltrates. B = Negative control (untreated): Features show some acinar cells with islet-cells showing mildly dispersed pyknotic nuclei (short arrow) and lymphocytic infiltrates as well as visible intralobular duct appearing fatty (long arrow). C = S. jamaicensis extract (30 mg/kg): Shows secretory acini with a pancreatic islet (long arrow). Histology reveals dispersed pyknotic nuclei with mild lymphocytic infiltrates (short arrow). D = S. jamaicensis extract (50 mg/kg): Features show some acinar cells with islet-cells showing mildly dispersed pyknotic nuclei (long arrow) and visible lymphocytic infiltrates (short arrow). E = S. jamaicensis extract (100 mg/kg): Features show some acinar cells with islet-cells showing mildly dispersed pyknotic nuclei (long arrow) and visible lymphocytic infiltrates (short arrow). [H & E staining; × 40 magnification]