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International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of Stachytarpheta jamaicensis extract on liver function of streptozotocin induced diabetic rats fed on a high fat diet

From: Anti-diabetic effect of Stachytarpheta jamaicensis on low dose streptozotocin-induced diabetic rats fed on a high-fat diet

Groups Dose mg/kg AST
(U/L)
ALT
(U/L)
ALP
(U/L)
GGT
(U/L)
Total protein
(g/dL)
Total bilirubin
(mg/dL)
Conjugated bilirubin (mg/dL) Unconjugated bilirubin (mg/dL)
Streptozotocin 35 67.00 ± 1.16a 21.67 ± 2.73a 28.33 ± 0.88a 1.05 ± 0.09a 38.00 ± 0.58a 0.16 ± 0.01a 0.09 ± 0.01a 0.07 ± 0.01a
Gliberclamide 10 32.70 ± 7.18b 22.60 ± 2.58a 12.62 ± 3.37b 0.53 ± 0.05c 11.22 ± 1.98c 0.04 ± 0.00c 0.02 ± 0.01c 0.02 ± 0.00d
S. jamaicensis 30 35.27 ± 3.59b 13.95 ± 1.10b 13.63 ± 2.74b 0.69 ± 0.05b 14.65 ± 1.09c 0.05 ± 0.02c 0.02 ± 0.01c 0.03 ± 0.00c
S. jamaicensis 50 42.04 ± 6.01c 23.55 ± 1.24a 18.25 ± 0.72b 0.29 ± 0.02c 23.41 ± 1.55c 0.06 ± 0.01b 0.02 ± 0.00c 0.03 ± 0.01c
S. jamaicensis 100 36.88 ± 3.10b 19.08 ± 1.75b 21.72 ± 3.40a 0.88 ± 0.03a 34.46 ± 0.53a 0.07 ± 0.02b 0.03 ± 0.00c 0.03 ± 0.00c
  1. Values are expressed as mean ± SEM, n = 10/group. Columns bearing different letters are significantly (p < 0.05) different, while those with the same letters are not significantly different. AST Aspartate amino transferase, ALT Alanine amino transferase, ALP Alkaline phosphatase, GGT Gamma-glutamyl transferase