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International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of Stachytarpheta jamaicensis extract on liver function of streptozotocin induced diabetic rats fed on a high fat diet

From: Anti-diabetic effect of Stachytarpheta jamaicensis on low dose streptozotocin-induced diabetic rats fed on a high-fat diet

Groups

Dose mg/kg

AST

(U/L)

ALT

(U/L)

ALP

(U/L)

GGT

(U/L)

Total protein

(g/dL)

Total bilirubin

(mg/dL)

Conjugated bilirubin (mg/dL)

Unconjugated bilirubin (mg/dL)

Streptozotocin

35

67.00 ± 1.16a

21.67 ± 2.73a

28.33 ± 0.88a

1.05 ± 0.09a

38.00 ± 0.58a

0.16 ± 0.01a

0.09 ± 0.01a

0.07 ± 0.01a

Gliberclamide

10

32.70 ± 7.18b

22.60 ± 2.58a

12.62 ± 3.37b

0.53 ± 0.05c

11.22 ± 1.98c

0.04 ± 0.00c

0.02 ± 0.01c

0.02 ± 0.00d

S. jamaicensis

30

35.27 ± 3.59b

13.95 ± 1.10b

13.63 ± 2.74b

0.69 ± 0.05b

14.65 ± 1.09c

0.05 ± 0.02c

0.02 ± 0.01c

0.03 ± 0.00c

S. jamaicensis

50

42.04 ± 6.01c

23.55 ± 1.24a

18.25 ± 0.72b

0.29 ± 0.02c

23.41 ± 1.55c

0.06 ± 0.01b

0.02 ± 0.00c

0.03 ± 0.01c

S. jamaicensis

100

36.88 ± 3.10b

19.08 ± 1.75b

21.72 ± 3.40a

0.88 ± 0.03a

34.46 ± 0.53a

0.07 ± 0.02b

0.03 ± 0.00c

0.03 ± 0.00c

  1. Values are expressed as mean ± SEM, n = 10/group. Columns bearing different letters are significantly (p < 0.05) different, while those with the same letters are not significantly different. AST Aspartate amino transferase, ALT Alanine amino transferase, ALP Alkaline phosphatase, GGT Gamma-glutamyl transferase