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International Journal of Phytomedicine and Phytotherapy

Table 3 Effect of Stachytarpheta jamaicensis extract on kidney function of streptozotocin induced diabetic rats fed on a high fat diet

From: Anti-diabetic effect of Stachytarpheta jamaicensis on low dose streptozotocin-induced diabetic rats fed on a high-fat diet

Groups

Dose mg/kg

Creatinine

(mg/dL)

Urea (mg/dL)

Bicarbonate

(mmol/L)

Na

(mmol/L)

K

(mmol/L)

Cl

(mmol/L)

Streptozotocin

35

0.27 ± 0.01a

37.17 ± 4.52a

19.92 ± 1.68a

99.92 ± 0.3a

29.40 ± 0.65a

80.25 ± 2.45a

Gliberclamide

10

0.18 ± 0.02c

30.83 ± 3.63b

24.09 ± 0.05b

105.7 ± 0.7b

23.08 ± 0.35b

61.58 ± 1.30c

S. jamaicensis

30

0.22 ± 0.01b

26.09 ± 0.92c

21.75 ± 1.11b

101.7 ± 1.6b

23.28 ± 0.67b

71.67 ± 1.54b

S. jamaicensis

50

0.22 ± 0.01b

26.42 ± 1.11c

21.75 ± 1.11b

106.7 ± 1.4b

23.81 ± 0.75b

63.92 ± 1.30c

S. jamaicensis

100

0.24 ± 0.01a

26.92 ± 0.53c

18.92 ± 0.63a

108.7 ± 0.1b

24.62 ± 0.59b

66.17 ± 1.83c

  1. Values are expressed as mean ± SEM, n = 10/group. Columns bearing different letters are significantly (p < 0.05) different, while those with the same letters are not significantly different