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International Journal of Phytomedicine and Phytotherapy

Table 2 Analysis of oral drug-likeness of the six bioactive compounds using Lipinski’s rule of five

From: Molecular interaction of bioactive compounds from Senecio biafrae leaf with α-amylase and α-glucosidase receptors

Bioactive Compounds Molecular weight (g/mol) Log P Number of hydrogen bond donor Number of hydrogen bond acceptor Molar refractivity
Caffeic acid 180.16 0.97 3 4 47.16
Gallic acid 170.12 0.21 4 5 38.47
Metformin 129.16 0.34 3 2 36.93
Quercetin 302.24 1.63 5 7 78.04
Rutin 617.66 − 92.39 10 14 147.66
Chlorogenic acid 354.31 0.87 6 9 83.50
Kaempferol 286.24 1.70 4 6 76.01