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International Journal of Phytomedicine and Phytotherapy

Table 6 Mean IPSS changes from baseline to 12 months estimated by ANCOVA (ITT set using LOCF)

From: Beneficial effects of pumpkin seed soft extract on lower urinary tract symptoms and quality of life in men with benign prostatic hyperplasia: a meta-analysis of two randomized, placebo-controlled trials over 12 months

Factor

Comparison

Estimate

95% CI

P value

Lower

Upper

Treatment

PSE vs. placebo

−0.66

−1.21

− 0.12

0.02

Study

Bach vs. GRANU study

−0.80

−1.40

−0.19

0.01

IPSS at BL

Per 1 point increase

−0.53

−0.63

− 0.43

<  0.01

Center size

Low- vs. high-recruiting

1.17

0.28

2.07

0.01

 

Medium- vs. high-recruiting

0.33

−0.29

0.95

0.30

  1. PSE pumpkin seed soft extract, BL baseline