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International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of ELEIG on hepatic function of SA-intoxicated experimental rats

From: Irvingia gabonensis leaf extract scavenges nitric oxide and hydrogen peroxide in vitro and modulates arsenic-induced hepatic oxidative stress in wistar rats

Groups

AST (U/L)

ALT (U/L)

ALP (U/L)

GGT (U/L)

TBIL (mg/dL)

DBIL (mg/dL)

1. Control

130.80 ± 64.39*

39.20 ± 5.26*

73.00 ± 6.20*

0.54 ± 0.10*

0.14 ± 0.06

0.04 ± 0.01

2. Arsenite only

220.20 ± 27.39#

83.40 ± 11.22#

170.60 ± 15.63#

1.19 ± 0.36#

0.24 ± 0.25

0.05 ± 0.02

3. PT at 100 mg/kgbw

203.80 ± 4.97#

47.80 ± 3.70#*

157.20 ± 6.76#*

0.67 ± 0.06*

0.10 ± 0.02

0.04 ± 0.01

4. PT at 200 mg/kgbw

194.50 ± 4.65#

44.00 ± 4.24*

144.25 ± 6.50#*

0.51 ± 0.09*

0.07 ± 0.02

0.05 ± 0.01

5. PT at 400 mg/kgbw

184.20 ± 10.92#*

38.80 ± 3.27*

134.40 ± 3.51#*

0.49 ± 0.03*

0.10 ± 0.06

0.05 ± 0.02

6. ST at 100 mg/kgbw

199.40 ± 14.14#

35.80 ± 6.30*

124.80 ± 4.21#*

0.52 ± 0.07*

0.13 ± 0.14

0.04 ± 0.01

7. ST at 200 mg/kgbw

191.50 ± 5.20#

39.75 ± 2.99*

114.00 ± 5.60#*

0.60 ± 0.17*

0.11 ± 0.04

0.03 ± 0.02

8. ST at 400 mg/kgbw

161.00 ± 9.13*

33.50 ± 6.45*

109.50 ± 23.85#*

0.54 ± 0.18*

0.09 ± 0.03

0.05 ± 0.01

9. ELEIG at 100 mg/kgbw

127.80 ± 10.96

35.20 ± 6.18

94.40 ± 9.13#

0.62 ± 0.10

0.60 ± 0.50#

0.06 ± 0.01

10. ELEIG at 200 mg/kgbw

101.80 ± 12.38

36.60 ± 2.30

86.00 ± 7.65#

0.60 ± 0.16

0.10 ± 0.08

0.04 ± 0.01

11. ELEIG at 400 mg/kgbw

85.80 ± 14.34#

31.40 ± 7.37#

86.20 ± 2.39#

0.64 ± 0.11

0.11 ± 0.06

0.05 ± 0.01

  1. Data are expressed as mean ± SD (n = 5); # p ˂ 0.05 compared with group 1; * p ˂ 0.05 compared with group 2; ELEIG Ethanol leaf extract of Irvingia gabonensis; mg / kgbw Milligram per kilogram body weight, PT Post-treatment, ST Simultaneous treatment.