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International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of ELEIG on hepatic function of SA-intoxicated experimental rats

From: Irvingia gabonensis leaf extract scavenges nitric oxide and hydrogen peroxide in vitro and modulates arsenic-induced hepatic oxidative stress in wistar rats

Groups AST (U/L) ALT (U/L) ALP (U/L) GGT (U/L) TBIL (mg/dL) DBIL (mg/dL)
1. Control 130.80 ± 64.39* 39.20 ± 5.26* 73.00 ± 6.20* 0.54 ± 0.10* 0.14 ± 0.06 0.04 ± 0.01
2. Arsenite only 220.20 ± 27.39# 83.40 ± 11.22# 170.60 ± 15.63# 1.19 ± 0.36# 0.24 ± 0.25 0.05 ± 0.02
3. PT at 100 mg/kgbw 203.80 ± 4.97# 47.80 ± 3.70#* 157.20 ± 6.76#* 0.67 ± 0.06* 0.10 ± 0.02 0.04 ± 0.01
4. PT at 200 mg/kgbw 194.50 ± 4.65# 44.00 ± 4.24* 144.25 ± 6.50#* 0.51 ± 0.09* 0.07 ± 0.02 0.05 ± 0.01
5. PT at 400 mg/kgbw 184.20 ± 10.92#* 38.80 ± 3.27* 134.40 ± 3.51#* 0.49 ± 0.03* 0.10 ± 0.06 0.05 ± 0.02
6. ST at 100 mg/kgbw 199.40 ± 14.14# 35.80 ± 6.30* 124.80 ± 4.21#* 0.52 ± 0.07* 0.13 ± 0.14 0.04 ± 0.01
7. ST at 200 mg/kgbw 191.50 ± 5.20# 39.75 ± 2.99* 114.00 ± 5.60#* 0.60 ± 0.17* 0.11 ± 0.04 0.03 ± 0.02
8. ST at 400 mg/kgbw 161.00 ± 9.13* 33.50 ± 6.45* 109.50 ± 23.85#* 0.54 ± 0.18* 0.09 ± 0.03 0.05 ± 0.01
9. ELEIG at 100 mg/kgbw 127.80 ± 10.96 35.20 ± 6.18 94.40 ± 9.13# 0.62 ± 0.10 0.60 ± 0.50# 0.06 ± 0.01
10. ELEIG at 200 mg/kgbw 101.80 ± 12.38 36.60 ± 2.30 86.00 ± 7.65# 0.60 ± 0.16 0.10 ± 0.08 0.04 ± 0.01
11. ELEIG at 400 mg/kgbw 85.80 ± 14.34# 31.40 ± 7.37# 86.20 ± 2.39# 0.64 ± 0.11 0.11 ± 0.06 0.05 ± 0.01
  1. Data are expressed as mean ± SD (n = 5); # p ˂ 0.05 compared with group 1; * p ˂ 0.05 compared with group 2; ELEIG Ethanol leaf extract of Irvingia gabonensis; mg / kgbw Milligram per kilogram body weight, PT Post-treatment, ST Simultaneous treatment.