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International Journal of Phytomedicine and Phytotherapy

Table 3 Effect of ELEIG on oxidative stress biomarkers of experimental rats

From: Irvingia gabonensis leaf extract scavenges nitric oxide and hydrogen peroxide in vitro and modulates arsenic-induced hepatic oxidative stress in wistar rats

Groups SOD (ng/mL) CAT (ng/mL) GPx (ng/mL) MDA (ng/mL)
1. Control 5.25 ± 0.22* 0.45 ± 0.33* 4.38 ± 0.51* 2.55 ± 0.27*
2. Arsenite only 1.18 ± 0.49# 2.91 ± 0.42# 0.14 ± 0.04# 6.96 ± 0.69#
3. PT at 100 mg/kgbw 2.09 ± 0.05#* 0.71 ± 0.46* 1.29 ± 0.78#* 6.21 ± 0.20#*
4. PT at 200 mg/kgbw 2.48 ± 0.14#* 1.05 ± 0.13#* 2.23 ± 0.14#* 6.08 ± 0.21#*
5. PT at 400 mg/kgbw 3.03 ± 0.18#* 1.39 ± 0.46#* 3.17 ± 0.74#* 5.50 ± 0.29#*
6. ST at 100 mg/kgbw 2.30 ± 0.28#* 1.60 ± 0.32#* 3.01 ± 0.26#* 5.82 ± 0.47#*
7. ST 200 mg/kgbw 2.94 ± 0.07#* 1.00 ± 0.08#* 3.53 ± 0.43#* 4.50 ± 0.35#*
8. ST at 400 mg/kgbw 3.12 ± 0.08#* 0.95 ± 0.06#* 3.21 ± 0.22#* 4.23 ± 0.82#*
9. ELEIG at 100 mg/kgbw 3.73 ± 0.19# 0.93 ± 0.12# 2.77 ± 0.94# 4.50 ± 0.73#
10. ELEIG at 200 mg/kgbw 3.92 ± 0.30# 0.91 ± 0.08# 4.05 ± 0.13 3.56 ± 0.57#
11. ELEIG at 400 mg/kgbw 4.14 ± 0.24# 0.88 ± 0.12# 4.52 ± 0.45 2.62 ± 0.44
  1. Data are expressed as mean ± SD (n = 5); # p ˂ 0.05 compared with group 1; * p ˂ 0.05 compared with group 2; ELEIG Ethanol leaf extract of Irvingia gabonensismg / kgbw Milligram per kilogram body weight, PT Post-treatment, ST Simultaneous treatment.