Antioxidant, cytotoxic, antibacterial and thrombolytic activities of Centella asiatica L.: possible role of phenolics and flavonoids

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 4 Antibacterial activity of the different fractions of C. asiatica

Test organism	Diameter of zone of inhibition (mm)
Test organism	MSF	PSF	CSF	ESF	K-30
Gram positive bacteria
Bacillus subtilis	6	7	5	-	37
Sarcina lutea	19	17	20	18	35
Staphylococcus aureus	18	19	20	16	37
Bacillus cereus	9	11	12	11	38
Sarcina sarcinaceae	14	-	23	20	32
Gram negative bacteria
Shigella dysenteriae	16	18	30	16	37
Vibrio mimicus	12	15	13	18	35
E. coli	18	12	22	24	31
Shigella shiga	18	12	21	22	30
Pseudomonas aeruginosa	19	-	20	23	27
Salmonella typhi	21	-	22	24	28

MSF Crude methanol extract, PSF Petroleum ether soluble fraction, CSF Chloroform soluble fraction, ESF Ethyl acetate soluble fraction. (-), sign indicates no activity. K-30, Kanamycin 30 μg /disc. All measurements were done in triplicate and average value was taken