Skip to main content

International Journal of Phytomedicine and Phytotherapy

Table 3 Effect of MECM on open and closed arm entry and time spent in both arms

From: Anxiolytic, analgesic and anti-inflammatory effects of Citrus maxima (Burm.) Merr. Seed extract in Swiss albino mice model

Treatment (mg/kg)

Open arm (OA)

Closed arm (CA)

Time spent (sec)

No. of entries

Time spent (sec)

No. of entries

Control-Tween 80 solution (10 ml/kg)

0.50 ± 0.32

0.80 ± 0.37

296.40 ± 2.01

14.60 ± 1.44

Standard-Diazepam (1 mg/kg)

52.65 ± 0.86***

8.60 ± 0.51***

213.78 ± 0.93***

2.80 ± 0.37**

MECM (200 mg/kg)

7.98 ± 1.07**

3.40 ± 0.40**

280.94 ± 0.47**

4.60 ± 0.51**

MECM (400 mg/kg)

8.41 ± 1.16**

3.80 ± 0.374**

283.962 ± 0.78**

4.00 ± 0.45**

  1. MECM Methanolic extract of seeds, SEM standard error of the mean
  2. All values are expressed as Mean ± SEM (N = 5)
  3. **p < 0.01, ***p < 0.001 were considered statistically significant compared to control