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Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 5 Effect of MECM on formalin-induced pain inhibition in Swiss Albino mice

From: Anxiolytic, analgesic and anti-inflammatory effects of Citrus maxima (Burm.) Merr. Seed extract in Swiss albino mice model

Treatment (mg/kg)

Mean pain scores

Early phase

% Inhibition

Late phase

% Inhibition

Control-Tween 80 solution (10 ml/kg)

52.88 ± 4.49

–

73.00 ± 4.87

–

Standard-Morphine sulfate (10 mg/kg)

8.60 ± 0.69**

83.74

2.12 ± 0.45***

97.09

MECM 200 mg/kg

10.36 ± 4.11**

80.41

2.71 ± 0.82***

96.29

MECM 400 mg/kg

9.19 ± 4.25**

82.62

2.33 ± 1.08***

96.81

  1. MECM Methanolic extract of seeds, SEM Standard error of the mean
  2. All values are expressed as Mean ± SEM (N = 5)
  3. **p < 0.01, ***p < 0.001 were considered statistically significant compared to control
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