International Journal of Phytomedicine and Phytotherapy
Table 6 Effect of MECM on formalin-induced paw edema inhibition
Treatment (mg/kg) | Pre-injection mean paw circumference (mm) | Post-injection mean paw circumference (mm) (% inhibition) | |||
|---|---|---|---|---|---|
1 hour | 2 hour | 3 hour | 4 hour | ||
Control-Tween 80 solution(10 ml/kg) | 8.10 ± 0.33 | 14.40 ± 0.40 - | 14.20 ± 0.37 - | 13.80 ± 0.20 - | 13.60 ± 0.29 - |
Standard-Indomethacin(10 mg/kg) | 8.90 ± 0.24 | 11.80 ± 0.34** (53.97%) | 11.30 ± 0.34** (60.66%) | 9.90 ± 0.19*** (82.46%) | 9.40 ± 0.19*** (90.91%) |
MECM 200 mg/kg | 7.60 ± 0.19 | 12.00 ± 0.27** (30.16%) | 11.40 ± 0.29** (37.70%) | 10.80 ± 0.25*** (43.86%) | 10.10 ± 0.24*** (54.55%) |
MECM 400 mg/kg | 7.20 ± 0.25 | 11.00 ± 0.57** (39.68%) | 10.40 ± 0.53** (47.54%) | 9.60 ± 0.40*** (57.89%) | 9.30 ± 0.41*** (61.82%) |