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International Journal of Phytomedicine and Phytotherapy

Fig. 3 | Clinical Phytoscience

Fig. 3

From: Black cohosh (Cimicifuga racemosa) is a non-estrogenic alternative to hormone replacement therapy

Fig. 3

a-c Histological appearance of mammary glands of (a) control ovx, (b) ovx + E2, (c) ovx + CR BNO 1055. Estradiol (E2) stimulated the number of lobuli in the mammary glands (b), but not in the sham (a) and in the BNO 1055 CR extract treated animals (c). D: duct; F: fat; L1: Lobulus 1; L2: Lobulus 2. d-f Histomorphometric evaluation of the histologic preparations after 3 months per food in ovx rats. d Effects of E2 and CR on number on lobulus 1/mm2; (e) Effects of E2 and CR on lobulus 2/mm2; (f) Effects of E2 and CR on number of ducts/mm2. E2 yielded a significant stimulation of lobuli type 1 (d) and 2 (e) and ducts (f) (*p < 0.05 vs control, ovx). CR: Cimicifuga racemosa BNO 1055; E2: Estradiol; lob: Lobulus; ovx: ovariectomised; sf: soy free food (*p < 0.05 vs. sham and vs. CR treated)

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