Fig. 1From: The premenstrual syndrome, premenstrual mastodynia, fibrocystic mastopathy and infertility have often common roots: effects of extracts of chasteberry (Vitex agnus castus) as a solutionIn women who do not suffer from premenstrual mastodynia LH pulses during the luteal phase occur relatively regular at 2–4 h intervals. These pulses are accompanied by prolactin pulses and are stimulatory to progesterone secretion by the corpus luteum (upper graph). In women suffering from premenstrual mastodynia the prolactin pulses are often of such a height that-at their peak time-one could suspect a pituitary prolactinoma. In the woman show in the lower graph LH pulses are of normal height gut the corpus luteum fails to respond with increade progesterone secretionBack to article page