Carbon tetrachloride induced hepatorenal toxicity in rats: possible protective effects of wild Pleurotus tuber-regium

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of P.tuber-regium on bilirubin, creatinine urea and fasting blood glucose

Treatment	Bilirubin	Creatinine	Urea	Fasting Blood Glucose
Treatment	(mg/dL)	(mg/dL)	(mg/dL)	(mg/dL)
Control	0.66 ± 0.07	0.76 ± 0.05	24.48 ± 4.70	75.67 ± 2.94
CCl₄ Only	1.21 ± 0.07 ^**	0.91 ± 0.04 ^**	45.76 ± 3.10 ^***	90.60 ± 4.62 ^***
CCl₄ + 100 mg P.t.	0.99 ± 0.04	0.82 ± 0.07	35.47 ± 11.68	79.25 ± 8.30 ^#
CCl₄ + 200 mg P.t.	0.78 ± 0.02 ^#	0.79 ± 0.03 ^#	27.31 ± 7.13 ^##	76.50 ± 3.79 ^##
CCl₄ + 500 mg P.t.	0.73 ± 0.09 ^#	0.76 ± 0.05 ^##	27.88 ± 6.44 ^##	76.25 ± 4.35 ^##
500 mg P.t. Only	0.66 ± 0.09 ^##	0.75 ± 0.06 ^##	24.25 ± 4.73 ^###	75.00 ± 3.92 ^##

Each value represents mean ± SD, n = 6. Values marked with an asterisk (*) differ significantly from control value (** p < 0.01, *** p < 0.001) while those marked with # differ significantly from CCl₄ only group (^# p < 0.05, ^## p < 0.01, ^### p < 0.001)