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International Journal of Phytomedicine and Phytotherapy

Table 3 Effect of P.tuber-regium on the superoxide dismutate (SOD) and malondialdehyde (MDA) in liver and kidney

From: Carbon tetrachloride induced hepatorenal toxicity in rats: possible protective effects of wild Pleurotus tuber-regium

 

Groups

Control

CCL4 Only

CCL4 + 100 mg P.t.

CCL4 + 200 mg P.t.

CCL4 + 500 mg P.t.

MDA (μmol/mg)

Kidney

1.40 ± 0.32

14.00 ± 3.50 ***

3.50 ± 0.61 ###

1.60 ± 0.36 ***

1.70 ± 0.15 ###

Liver

1.90 ± 0.42

14.00 ± 2.60 ***

10.00 ± 1.80 ***

8.90 ± 1.00 ** #

8.60 ± 1.5 ** ##

SOD (μg/mg protein)

Kidney

8.49 ± 0.38

2.78 ± 0.30 ***

3.18 ± 0.31 ***

5.31 ± 0.37 ***###

6.48 ± 0.50 *** ###

Liver

7.58 ± 0.59

1.48 ± 0.33 ***

1.65 ± 0.48 ***

3.60 ± 0.36 *** ###

3.88 ± 0.47 *** ###

  1. Each value represents mean ± SD, n = 6. Values marked with an asterisk (*) differ significantly from control value (** p < 0.01, *** p < 0.001) while those marked with # differ significantly from CCl4 only group (# p < 0.05, ## p < 0.01, ### p < 0.001)