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International Journal of Phytomedicine and Phytotherapy

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Table 4 Effect of BR extract on STZ induced diabetes in rats

From: Biological activity of Bauhinia racemosa against Diabetes and Interlinked Disorders like Obesity and Hyperlipidemia

S. N. Group Dose (mg/kg) Blood Glucose Level (mg/dL)
Day 0 Day 7 Day 14 Day 21 Day 28
  NC untreated 79.12 ± 0.78 89.83 ± 1.10 86.36 ± 1.03 87.60 ± 1.43 87.46 ± 2.37
  DC vehicle 80.20 ± 0.56 370.04 ± 6.28 338.30 ± 13.18 297.97 ± 2.66 297.76 ± 2.97
  RG 5.0 81.35 ± 0.49 353.33 ± 3.49** 261.48 ± 2.69*** 182.82 ± 3.18*** 122.70 ± 3.26***
  BR-1 250 81.37 ± 0.47 361.00 ± 2.80 281.10 ± 2.55*** 204.49 ± 3.79*** 143.88 ± 2.06***
  BR-2 500 79.72 ± 0.74 355.41 ± 3.17* 264.23 ± 2.56*** 191.24 ± 2.69*** 134.70 ± 1.58***
  1. NC = Normal control, DC = Diabetic control, RG = Reference group (glibenclamide), BR-1 = BR extract in dose of 250 mg/kg, BR-2 = BR extract in dose of 500 mg/kg
  2. Values are expressed as mean ± SEM (Number of animals = 6) significantly different at *p < 0.05, **p < 0.01, ***p < 0.001