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International Journal of Phytomedicine and Phytotherapy

Table 8 The effect of MEPH on hole-board test in mice

From: Evaluation of sedative and anxiolytic activities of methanol extract of leaves of Persicaria hydropiper in mice

Treatment

Dose (mg/kg)

Number of head dips

Control

0.1 ml/mouse

42.40 ± 0.92

Diazepam

1

12.20 ± 0.58***

MEPH

50

40.40 ± 0.51

MEPH

200

29.00 ± 0.54***

MEPH

350

21.00 ± 0.63***

MEPH

500

15.20 ± 0.58***

  1. Each value is presented as the mean ± SEM (n = 10), MEPH = Methanol extract of Persicaria hydropiper leaves. “***p < 0.001, **p < 0.01, *p < 0.05 vs control group (Dunnett’s test)”