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International Journal of Phytomedicine and Phytotherapy

Table 4 Toxicity and ADME analysis of the phytoconstitiuents isolated from Piper sylvaticum by Swiss ADME Analysis and Molinspiration Cheminformatics software

From: Anthelmintic activity of Piper sylvaticum Roxb. (family: Piperaceae): In vitro and in silico studies

Compound name Molecular weighta (g/mol) H-donorb H-acceptorc LogP valued Molar refractivitye
Piperine 285.34 0 3 3.33 85.47
Piperlonguminine 273.33 1 3 3.30 78.77
N-isobutyl deca-trans-2-trans-4-dienamide 223.35 1 1 4.26 71.47
  1. aMolecular weight accepted range < 500
  2. bHydrogen bond donor acceptable range ≤ 5
  3. cHydrogen bond acceptor acceptable range ≤ 10
  4. dHigh lipophilicity (expressed as LogP, Acceptable range < 5)
  5. eMolar refractivity should be between 40 and 130