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International Journal of Phytomedicine and Phytotherapy

Clinical Phytoscience Cover Image

Table 5 Effect of S. nigrum on CCl4 -induced changes in SDH and ATPase activities

From: Solanum nigrum confers protection against CCl4-induced experimental hepatotoxicity by increasing hepatic protein synthesis and regulation of energy metabolism

Experimental groups SDH ATPase
Control
 1. Untreated 61.12 ± 2.12 0.35 ± 0.12
 2. Olive oil 61.89 ± 1.12 0.35 ± 0.09
 3. S. nigrum (SN) 61.01 ± 0.44 0.34 ± 0.11
Carbon Tetrachloride (CCl4) -Treated
 4. CCl4 33.23 ± 1.24a* 0.17 ± 0.02a*
(V) CCl4 + Solanum Nigrum (SN) Extract-Treated
 5. CCl4 + SN100 43.28 ± 0.66b* 0.24 ± 0.55b*
 6. CCl4 + SN200 46.02 ± 0.54b* 0.25 ± 0.90b*
 7. CCl4 + SN300 47.29 ± 0.33b* 0.28 ± 0.76b*
  1. Results are expressed as mean ± SEM; n = 10
  2. No significant difference was noted between groups 1–3
  3. aas compared between vehicle control (group 2) and toxin-treated (group 4),
  4. bas compared between toxin-treated (group 4) and toxin - + antidote-treated (groups 5–7)
  5. Level of significance *p < 0.001
  6. Units: SDH - μg formazon formed/mg protein/15 min; ATPase - μmoles i.p. released/mg protein/30 min