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International Journal of Phytomedicine and Phytotherapy

Table 1 Effect of Ganoderma lucidum on Escape Latency (sec) in Morris Water Maze

From: Effect of Ganoderma lucidum on memory and learning in mice

Treatment group Dose EL (Sec) Day 6 EL (Sec) Day 7 EL (Sec) Day 8 EL (Sec) Day 9
Control 10 ml/Kg 28.4 ± 2.4 14.4 ± 1.2 13.2 ± 1.1 12.4 ± 0.9
Scopolamine 0.4 mg/Kg 70.6 ± 2.5*** 71.6 ± 3.4*** 69.6 ± 4.4*** 67.6 ± 4.8***
Physo + Scop 0.1 mg/Kg + 0.4 mg/Kg 27.4 ± 1.9 12.8 ± 0.9 11.8 ± 0.9c 11.0 ± 0.8c
GLE 150 mg + Scop 150 mg/Kg + 0.4 mg/Kg 29.4 ± 2.7 26.4 ± 1.8 12.8 ± 0.8 13.6 ± 0.8c
GLE 300 mg + Scop 300 mg/Kg + 0.4 mg/Kg 27 ± 3.5 23.2 ± 2.0 10.8 ± 0.5c** 10.0 ± 0.3c**
  1. Animals per group (n) = 6; The values are mean ± SEM (One-way ANOVA followed by Tukey’s Post hoc test)
  2. ap < 0.05, bp < 0.01, cp < 0.001 when compared with scopolamine alone treated group
  3. *p < 0.05, **p < 0.01, ***p < 0.0001 when compared with DW treated (control) group
  4. DW distilled water, GLE 150 Ganoderma lucidum extract (150 mg/kg), GLE 300 Ganoderma lucidum extract 300/kg, Scop Scopolamine, Physo Physostigmine