Protective effect of crude sulphated polysaccharides from Sargassum Swartzii (Turn.) C.Ag. against acetaminophen induced liver toxicity in rats

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of Crude Sulphated Polysaccharides of Sargassum swartzii on Glucose, Urea, Creatinine, Triglycerides and Cholesterol in Acetaminophen-Intoxicated Rats

Groups	Glucose (mg/dl)	Triglycerides (mg/dl)	Cholesterol (mg/dl)	Urea (mg/dl)	Creatinine (mg/dl)
Normal control	108.6^c ± 3.5	84^b ± 5.2	84.6^a ± 2.3	30^d ± 1	0.9^c ± 0.1
Acetaminophen (AAP) control	162^a ± 6.5	167.3^a ± 10.06	64.6^bc ± 5.8	64^a ± 6.2	1.23^a ± 0.11
Silymarin (35 mg/kg) + AAP	118.3^bc ± 8.6	92^b ± 23.06	68.6^b ± 4.04	35^cd ± 2.6	1.03^bc ± 0.057
S. swartzii EW₁ + AAP	127^b ± 7.5	108^b ± 17.08	65^ac ± 3.6	38.6^bc ± 2.5	1^bc ± 0.1
S. swartzii EW₂ + AAP	169^a ± 8	106^b ± 13.11	58.3^c ± 3.7	43.6^b ± 2.08	1.1^ab ± 0

The values are expressed as means ± Standard error (n = 6 animals per group)
The values having the same superscript within the column are not significantly (p < 0.05) different according to Duncan’s multiple range test