Anti-diarrheal activity and brine shrimp lethality bioassay of methanolic extract of Cordyline fruticosa (L.) A. Chev. leaves

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 3 Effect of MCFL on charcoal meal test

Groups	Dose	Mean length of intestine (cm) ± SEM	Mean distance traveled by charcoal meal (cm) ± SEM	Mean% movement of charcoal ±SEM after 30 min	% Inhibition
Control	10 mL/kg	43.60 ± 1.56	30.40 ± 1.93	69.74 ± 3.71	0.00 ± 0.00
Atropine sulfate	5 mg/kg	48.20 ± 2.28	12.74 ± 3.09^∗	27.26 ± 8.12^∗	58.84 ± 9.11^∗
MCFL	200 mg/kg	44.30 ± 1.65	25.9 ± 1.41	52.71 ± 7.03	14.46 ± 4.59
MCFL	400 mg/kg	44.80 ± 2.10	21.5 ± 2.86^∗	47.89 ± 5.66^∗	26.32 ± 12.92
MCFL	800 mg/kg	46.90 ± 1.98	19.3 ± 1.40^∗	40.83 ± 2.14^∗	34.87 ± 6.82^∗

cm, centimeter; the values are mean ± SEM., n = 5. ^∗P < 0.05 vs control (Dunnett’s t-test). MCFL Methanolic extract of Cordyline fruticosa leaves