Anti-inflammatory, antinociceptive and antidiarrhoeal activities of methanol and ethyl acetate extract of Hemigraphis alternata leaves in mice

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of standard and MHAL and EAHAL on Xylene induced ear edema test

Treatment groups	Dose	Ear weight Differences (mg)	% of inhibition	p value
Control	10 mL/kg	11.60 ± 1.12	0.00 ± 0.00	–
DS	100 mg/kg	5.60 ± 0.93^***	46.85 ± 13.62^***	.000
MHAL	200 mg/kg	9.00 ± 0.71	20.12 ± 7.81	.103
MHAL	400 mg/kg	7.40 ± 0.75^**	34.10 ± 8.10^**	.008
EAHAL	200 mg/kg	8.17 ± 0.98^*	32.68 ± 4.90^*	.023
EAHAL	400 mg/kg	6.75 ± 0.85^**	35.15 ± 11.78^**	.004

All of the experimental values are denoted as mean ± SEM. MHAL = Methanol extract of Hemigraphis alternata leaves. EAHAL = Ethyl acetate extract of Hemigraphis alternata leaves. “^*푃 < 0.05, ^** 푃 < 0.01, ^*** 푃 < 0.001 versus control group (Dunnett’s test)”