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International Journal of Phytomedicine and Phytotherapy

Table 5 Effect of standard and MHAL and EAHAL in acetic acid-induced writhing test

From: Anti-inflammatory, antinociceptive and antidiarrhoeal activities of methanol and ethyl acetate extract of Hemigraphis alternata leaves in mice

Treatment groups

Dose

No. of writhing

% of inhibition

p value

Control

10 mL/kg

37.60 ± 2.16

0.00 ± 0.00

DS

100 mg/kg

9.40 ± 1.33***

74.15 ± 4.86***

.000

MHAL

200 mg/kg

29.60 ± 2.09*

20.39 ± 6.83*

.041

MHAL

400 mg/kg

19.20 ± 2.24***

49.17 ± 4.41***

.000

EAHAL

200 mg/kg

25.50 ± 3.11**

30.73 ± 7.52**

.002

EAHAL

400 mg/kg

18.00 ± 1.58***

54.00 ± 2.38***

.000

  1. All of the experimental values are denoted as mean ± SEM. MHAL = Methanol extract of Hemigraphis alternata leaves. EAHAL = Ethyl acetate extract of Hemigraphis alternata leaves. “*푃 < 0.05, ** 푃 < 0.01, *** 푃 < 0.001 versus control group (Dunnett’s test)”