Anti-inflammatory, antinociceptive and antidiarrhoeal activities of methanol and ethyl acetate extract of Hemigraphis alternata leaves in mice

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 6 Effect of standard and MHAL and EAHAL in Castor oil induced diarrhoeal model

Treatment groups	Dose	No. of diarrhoeal feces	% of inhibition	p value
Control	10 mL/kg	9.00 ± 1.58	0.00 ± 0.00	–
Loperamide HCl	3 mg/kg	2.20 ± 0.73^***	74.31 ± 8.72^***	.001
MHAL	200 mg/kg	5.20 ± 1.39^*	44.05 ± 8.55^*	.046
MHAL	400 mg/kg	3.20 ± 1.07^**	67.73 ± 5.77^**	.003
EAHAL	200 mg/kg	6.67 ± 0.80	29.79 ± 7.62	.212
EAHAL	400 mg/kg	3.75 ± 0.85^**	51.19 ± 7.81^**	.010

All of the experimental values are denoted as mean ± SEM. MHAL = Methanol extract of Hemigraphis alternata leaves. EAHAL = Ethyl acetate extract of Hemigraphis alternata leaves. “^*푃 < 0.05, ^** 푃 < 0.01, ^*** 푃 < 0.001 versus control group (Dunnett’s test)”