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International Journal of Phytomedicine and Phytotherapy

Table 7 Effects of AGE on kidney indicators of oxidative stress and lipid peroxidation in Wistar rats with Pb-induced kidney injury

From: Aqueous garlic extract improves renal clearance via vasodilatory/antioxidant mechanisms and mitigated proteinuria via stabilization of glomerular filtration barrier

Indicators of oxidative stressIndicator of lipid peroxidation
Groups (n = 5)GSH (μg/mg protein)SOD (mM/mg protein)CAT (μmol/min/mg protein)TBARS (nmol/mg protein)
[1] Control3.36 ± 0.110.77 ± 0.022.30 ± 0.0525.57 ± 0.88
[2] Pb0.95 ± 0.07a0.22 ± 0.01a0.76 ± 0.04a74.88 ± 1.53a
[3] Pb + Recovery1.20 ± 0.07a0.25 ± 0.02a0.98 ± 0.07ab65.24 ± 1.90ab
[4] Pb + 100 mg/kg AGE2.44 ± 0.15abc0.55 ± 0.02abc1.60 ± 0.06abc44.24 ± 1.95abc
[5] Pb + 200 mg/kg AGE3.24 ± 0.07bcd0.69 ± 0.02abcd2.20 ± 0.07bcd26.52 ± 0.36bcd
[6] Pb + 400 mg/kg AGE3.51 ± 0.09bcd0.76 ± 0.02bcde2.22 ± 0.08bcd23.08 ± 1.10bcd
  1. Each value represents mean ± Standard Error of Mean (S.E.M.) at p < 0.05
  2. a = significantly different from control group [1],
  3. b = significantly different from Pb group [2],
  4. c = significantly different from Pb + recovery group [3],
  5. d = significantly different from Pb + 100 mg/kg group [4], and
  6. e = significantly different from Pb + 200 mg/kg group [5]