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Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 7 Effects of AGE on kidney indicators of oxidative stress and lipid peroxidation in Wistar rats with Pb-induced kidney injury

From: Aqueous garlic extract improves renal clearance via vasodilatory/antioxidant mechanisms and mitigated proteinuria via stabilization of glomerular filtration barrier

Indicators of oxidative stress

Indicator of lipid peroxidation

Groups (n = 5)

GSH (μg/mg protein)

SOD (mM/mg protein)

CAT (μmol/min/mg protein)

TBARS (nmol/mg protein)

[1] Control

3.36 ± 0.11

0.77 ± 0.02

2.30 ± 0.05

25.57 ± 0.88

[2] Pb

0.95 ± 0.07a

0.22 ± 0.01a

0.76 ± 0.04a

74.88 ± 1.53a

[3] Pb + Recovery

1.20 ± 0.07a

0.25 ± 0.02a

0.98 ± 0.07ab

65.24 ± 1.90ab

[4] Pb + 100 mg/kg AGE

2.44 ± 0.15abc

0.55 ± 0.02abc

1.60 ± 0.06abc

44.24 ± 1.95abc

[5] Pb + 200 mg/kg AGE

3.24 ± 0.07bcd

0.69 ± 0.02abcd

2.20 ± 0.07bcd

26.52 ± 0.36bcd

[6] Pb + 400 mg/kg AGE

3.51 ± 0.09bcd

0.76 ± 0.02bcde

2.22 ± 0.08bcd

23.08 ± 1.10bcd

  1. Each value represents mean ± Standard Error of Mean (S.E.M.) at p < 0.05
  2. a = significantly different from control group [1],
  3. b = significantly different from Pb group [2],
  4. c = significantly different from Pb + recovery group [3],
  5. d = significantly different from Pb + 100 mg/kg group [4], and
  6. e = significantly different from Pb + 200 mg/kg group [5]
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