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International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of Stokeyia indica ethanol extract on serum biochemical parameters in normal and acetaminophen intoxicated rats

From: Protective role of Stokeyia indica in liver dysfunction and associated complications in acetaminophen intoxicated rats

Groups

ALAT (U/L)

ASAT (U/L)

ALP (U/L)

LDH (U/L)

Total bilirubin (mg/dl)

Direct bilirubin (mg/dl)

Creatinine (mg/dl)

Urea (mg/dl)

Glucose (mg/dl)

Cholesterol (mg/dl)

Triglyceride (mg/dl)

Control

24.2 ± 0.9c

75.5 ± 2.6c

94.2 ± 2.5b

256.5 ± 4.6c

0.45 ± 0.06b

0.1 ± 0c

0.82 ± 0.05b

23.7 ± 3.3c

91.2 ± 1.7b

87.2 ± 0.9a

97.0 ± 4.1b

Acetaminophen treated rats (1 g/kg)

66.0 ± 1.8a

289.5 ± 2.1a

142.0 ± 4.9a

386. 2 ± 2.6a

0.8 ± 0.08a

0.3 ± 0.01a

1.25 ± 0.06a

48.5 ± 1.9a

137 ± 1.8a

54.5 ± 1.3d

121.2 ± 2.9a

Stokeyia indica pre-treated + acetaminophen

33.2* ± 1.70b

205.2* ± 4.1b

96.5* ± 5.9b

290.0* ± 3.7b

0.50* ± 0.1b

0.15* ± 0.06bc

0.85* ± 0.06b

30.2* ± 1.2b

80.2* ± 2.6c

67.5* ± 2.1b

91.2* ± 2.7c

S. indica (200 mg/kg)

20.5 ± 1.0d

66.5 ± 1.7d

82.0 ± 3.6c

227.0 ± 5.0d

0.45 ± 0.1b

0.2 ± 0.08b

0.7 ± 0.08c

28.2 ± 2.4b

76.2 ± 3.1d

63.0 ± 1.4c

70.0 ± 1.6d

  1. The values are expressed as means ± Standard Deviation (n = 6 animals per group)
  2. Means values in column bearing same superscript letter are not significantly (p < 0.05) different according to Duncan’s Multiple Range Test
  3. *Significant at p < 0.05 as compared to acetaminophen control