Total phenolic and flavonoid contents and antioxidant, anti-inflammatory, analgesic, antipyretic and antidiabetic activities of Cordia myxa L. leaves

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 9 Results of the anti-pyretic activity of the total ethanol extract and the different fractions of C. myxa L. leaves using yeast-induced pyrexia method

Group	Rectal temperature (°C)
Group	0 h	30 min	1 h	2 h	3 h	4 h	5 h
Control (−ve)	39.83 ± 0.10	39.88 ± 0.05	39.88 ± 0.05	39.88 ± 0.05	39.83 ± 0.10	39.88 ± 0.05	39.28 ± 0.09
Total extract (350 mg/kg)	39.75 ± 0.13	38.63 ± 0.39 ^***	38.53 ± 0.50 ^**	37.73 ± 0.17 ^***	37.65 ± 0.13 ^***	37.83 ± 0.10 ^***	38.00 ± 0.27 ^***
Petroleum ether fraction (350 mg/kg)	39.83 ± 0.10	39.20 ± 0.60	38.80 ± 0.34 ^***	37.68 ± 0.21^***	37.60 ± 0.08 ^***	37.43 ± 0.10 ^***	38.08 ± 0.41 ^***
Dichloromethane fraction (350 mg/kg)	39.83 ± 0.10	39.25 ± 0.17 ^***	38.53 ± 0.10 ^***	37.78 ± 0.15 ^***	37.63 ± 0.13 ^***	37.60 ± 0.08 ^***	38.88 ± 0.47 ^**
Ethyl acetate fraction (350 mg/kg)	39.80 ± 0.14	38.73 ± 0.17 ^***	38.73 ± 0.17 ^***	37.73 ± 0.40 ^***	37.45 ± 0.31 ^***	37.70 ± 0.18 ^***	38.25 ± 0.41 ^***
Butanol fraction (350 mg/kg)	39.85 ± 0.10	39.73 ± 0.17	39.13 ± 0.17 ^***	38.33 ± 0.35 ^***	37.73 ± 0.17 ^***	37.78 ± 0.15 ^***	38.75 ± 0.19 ^***
Acetyl salicylic acid(330 mg/kg)	39.83 ± 0.10	38.28 ± 0.49 ^***	37.58 ± 0.10 ^***	37.48 ± 0.05 ^***	37.43 ± 0.17 ^***	37.13 ± 0.15 ^***	37.08 ± 0.10 ^***

The results are presented as the mean ± S.E.M. Differences with respect to the control group were calculated using the student’s T-test (*P > 0.05, **P < 0.01, ***P < 0.001)