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International Journal of Phytomedicine and Phytotherapy

Table 9 Results of the anti-pyretic activity of the total ethanol extract and the different fractions of C. myxa L. leaves using yeast-induced pyrexia method

From: Total phenolic and flavonoid contents and antioxidant, anti-inflammatory, analgesic, antipyretic and antidiabetic activities of Cordia myxa L. leaves

Group Rectal temperature (°C)
0 h 30 min 1 h 2 h 3 h 4 h 5 h
Control (−ve) 39.83 ± 0.10 39.88 ± 0.05 39.88 ± 0.05 39.88 ± 0.05 39.83 ± 0.10 39.88 ± 0.05 39.28 ± 0.09
Total extract (350 mg/kg) 39.75 ± 0.13 38.63 ± 0.39 *** 38.53 ± 0.50 ** 37.73 ± 0.17 *** 37.65 ± 0.13 *** 37.83 ± 0.10 *** 38.00 ± 0.27 ***
Petroleum ether fraction (350 mg/kg) 39.83 ± 0.10 39.20 ± 0.60 38.80 ± 0.34 *** 37.68 ± 0.21*** 37.60 ± 0.08 *** 37.43 ± 0.10 *** 38.08 ± 0.41 ***
Dichloromethane fraction (350 mg/kg) 39.83 ± 0.10 39.25 ± 0.17 *** 38.53 ± 0.10 *** 37.78 ± 0.15 *** 37.63 ± 0.13 *** 37.60 ± 0.08 *** 38.88 ± 0.47 **
Ethyl acetate fraction (350 mg/kg) 39.80 ± 0.14 38.73 ± 0.17 *** 38.73 ± 0.17 *** 37.73 ± 0.40 *** 37.45 ± 0.31 *** 37.70 ± 0.18 *** 38.25 ± 0.41 ***
Butanol fraction (350 mg/kg) 39.85 ± 0.10 39.73 ± 0.17 39.13 ± 0.17 *** 38.33 ± 0.35 *** 37.73 ± 0.17 *** 37.78 ± 0.15 *** 38.75 ± 0.19 ***
Acetyl salicylic acid(330 mg/kg) 39.83 ± 0.10 38.28 ± 0.49 *** 37.58 ± 0.10 *** 37.48 ± 0.05 *** 37.43 ± 0.17 *** 37.13 ± 0.15 *** 37.08 ± 0.10 ***
  1. The results are presented as the mean ± S.E.M. Differences with respect to the control group were calculated using the student’s T-test (*P > 0.05, **P < 0.01, ***P < 0.001)