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International Journal of Phytomedicine and Phytotherapy

Table 3 Effects of methanol extract of J. secunda leaves on hematological parameters of rats induced with inflammation using formaldehyde

From: Evaluation of anti-inflammatory activity of Justicia secunda Vahl leaf extract using in vitro and in vivo inflammation models

Parameters

Normal

Untreated control

10 mg/kg b.w. Diclofenac sodium

100 mg/kg b.w. MEJSL

300 mg/kg b.w. MEJSL

RBC (1012/L)

6.43 ± 0.69

6.19 ± 0.04α

6.16 ± 0.75α

7.09 ± 0.53β

7.87 ± 0.10β

HCT (%)

41.96 ± 5.84

38.30 ± 1.42α

40.60 ± 1.13α

42.14 ± 1.09β

44.92 ± 1.31β

HGB (g/dl)

13.50 ± 1.07

12.36 ± 0.94α

12.56 ± 0.31α

14.36 ± 0.87β

14.66 ± 0.36 β

PLT (109/L)

489.00 ± 67.32

339.40 ± 72.58α

335.20 ± 83.65 α

527.80 ± 48.36 β

619.40 ± 36.44 β

WBC (109/L)

9.22 ± 3.26

11.18 ± 0.12Ω

9.66 ± 0.16

9.04 ± 0.26*

8.46 ± 1.53*

LYM (109/L)

7.06 ± 2.11

8.25 ± 0.99 Ω

7.50 ± 1.63

7.40 ± 0.78*

7.10 ± 1.39*

GRAN (109/L)

1.40 ± 0.85

0.74 ± 0.12 Ω

0.84 ± 0.21

0.62 ± 0.06*

0.44 ± 0.07*

EBM (109/L)

0.76 ± 0.32

2.79 ± 0.10 Ω

1.32 ± 0.35

1.02 ± 0.15*

0.92 ± 0.13*

  1. RBC red blood cells, HCT hematocrit, PLT platelet, WBC white blood cells, HGB hemoglobin, LYM lymphocytes, GRAN granulocytes, EBM eosinophil, basophil, and monocyte, MEJSL methanol extract of Justicia secunda leaves
  2. Different symbols across row indicate significantly different at P < 0.05