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International Journal of Phytomedicine and Phytotherapy

Table 3 Effects of methanol extract of J. secunda leaves on hematological parameters of rats induced with inflammation using formaldehyde

From: Evaluation of anti-inflammatory activity of Justicia secunda Vahl leaf extract using in vitro and in vivo inflammation models

ParametersNormalUntreated control10 mg/kg b.w. Diclofenac sodium100 mg/kg b.w. MEJSL300 mg/kg b.w. MEJSL
RBC (1012/L)6.43 ± 0.696.19 ± 0.04α6.16 ± 0.75α7.09 ± 0.53β7.87 ± 0.10β
HCT (%)41.96 ± 5.8438.30 ± 1.42α40.60 ± 1.13α42.14 ± 1.09β44.92 ± 1.31β
HGB (g/dl)13.50 ± 1.0712.36 ± 0.94α12.56 ± 0.31α14.36 ± 0.87β14.66 ± 0.36 β
PLT (109/L)489.00 ± 67.32339.40 ± 72.58α335.20 ± 83.65 α527.80 ± 48.36 β619.40 ± 36.44 β
WBC (109/L)9.22 ± 3.2611.18 ± 0.12Ω9.66 ± 0.169.04 ± 0.26*8.46 ± 1.53*
LYM (109/L)7.06 ± 2.118.25 ± 0.99 Ω7.50 ± 1.637.40 ± 0.78*7.10 ± 1.39*
GRAN (109/L)1.40 ± 0.850.74 ± 0.12 Ω0.84 ± 0.210.62 ± 0.06*0.44 ± 0.07*
EBM (109/L)0.76 ± 0.322.79 ± 0.10 Ω1.32 ± 0.351.02 ± 0.15*0.92 ± 0.13*
  1. RBC red blood cells, HCT hematocrit, PLT platelet, WBC white blood cells, HGB hemoglobin, LYM lymphocytes, GRAN granulocytes, EBM eosinophil, basophil, and monocyte, MEJSL methanol extract of Justicia secunda leaves
  2. Different symbols across row indicate significantly different at P < 0.05