Table 2 Effect of combined administration of lisinopril and ethanolic extract of E. chlorantha on serum biomarkers of liver function

NC

Distilled water only

30.36 ± 2.45^a

29.69 ± 0.83^a

1.04 ± 0.76^a

0.25 ± 0.84^a

0.79 ± 0.82^d

0.93 ± 0.31^a

DM

STZ-fructose+ distilled water

77.68 ± 4.67^e

85.80 ± 1.04^d

1.54 ± 0.54^d

1.14 ± 0.60^d

1.50 ± 0.47^a

2.46 ± 0.53^c

T1

Extract only

37.10 ± 2.68^ab

42.60 ± 4.70^b

1.14 ± 0.16^bc

0.52 ± 0.15^bc

0.90 ± 0.10^c

1.22 ± 0.18^a

T2

Glucophage only

44.70 ± 1.23^bc

39.38 ± 3.79^ab

1.07 ± 0.74^b

0.48 ± 0.03^bc

0.93 ± 0.29^d

1.14 ± 0.35^a

T3

Extract + Lisinopril

48.70 ± 0.96^c

56.98 ± 1.72^c

1.29 ± 0.53^c

0.71 ± 0.26^c

0.78 ± 0.13^b

1.62 ± 0.59^a

T4

Glucophage + Lisinopril

47.42 ± 2.03^b

49.12 ± 2.15^bc

1.26 ± 0.65^c

0.68 ± 0.31^c

0.81 ± 0.03^b

1.05 ± 0.44^a

T5

Lisinopril only

60.25 ± 4.63^d

55.88 ± 2.07^c

1.39 ± 0.05^d

0.97 ± 0.13^d

1.07 ± 0.20^b

1.83 ± 0.34^b