Evaluation of anti-obesity potential of aqueous extract of Achyranthes aspera Linn. in high fat diet induced obese rats

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 1 Fat Pad Weights, Adipocyte Size and Organ Weights of Experimental Rats

Experimental Groups	Group I	Group II	Group III	Group IV	Group V	Group VI
Mesenteric WAT (g)	3.38 ± 0.32	12.76 ± 0.41^#	10.15 ± 0.9	9.14 ± 0.9	8.28 ± 0.25*	4.09 ± 0.25**
Retro-peritoneal WAT (g)	4.83 ± 0.18	14.65 ± 0.55^#	12.62 ± 0.48	10.25 ± 0.31	9.86 ± 0.33*	5.26 ± 0.23**
Perirenal WAT (g)	0.68 ± 0.07	4.21 ± 0.18^#	4.03 ± 0.11	3.52 ± 0.15	2.53 ± 0.05*	0.93 ± 0.03**
Adipocyte Size (Area - μm²)	29,605.66 ± 3967	87,868.06 ± 8121^#	77,476.05 ± 7698	61,075.34 ± 7072	57,441.08 ± 4479*	33,008.04 ± 6064**
Liver (g)	5.35 ± 0.14	9.96 ± 0.18^#	7.68 ± 0.06	6.86 ± 0.09	6.13 ± 0.11*	5.55 ± 0.11**
Kidney (g)	1.35 ± 0.06	2.29 ± 0.08^#	1.95 ± 0.11	1.75 ± 0.03	1.53 ± 0.06*	1.34 ± 0.03**
Heart (g)	0.62 ± 0.02	1.03 ± 0.06^#	0.93 ± 0.05	0.83 ± 0.03	0.74 ± 0.03*	0.63 ± 0.07**
Spleen (g)	0.53 ± 0.02	0.95 ± 0.04^#	0.78 ± 0.06	0.67 ± 0.03	0.62 ± 0.05*	0.52 ± 0.04**

Values are mean ± S.E.M of 6 rats; ^#p < 0.01 vs Normal Control (Group I); *p < 0.05 vs Obese Control (Group II); **p < 0.01 vs Obese Control (Group II)