International Journal of Phytomedicine and Phytotherapy
Table 5 Comparative studies of herbal products in acute rhinosinusitis
From: Evidence-based management of acute rhinosinusitis with herbal products
Study | Study design | Population | Sample size | Main findings |
|---|---|---|---|---|
Tesche S, et al. 2008 [43] | Double-blind randomized clinical trial | Patients suspected of having acute rhinosinusitis | n = 75 with 5-component herbal preparation n = 75 with cineole | Primary outcome: The change in symptom-sum score from baseline to Day 7 was higher in the cineole group (− 11.0 ± 3.3) than in the other group (− 8.0 ± 3.0) (p < 0.0001). Secondary outcome: Changes in individual components of symptom-sum score were higher in the cineole group than in the other group. |
Gottschlich S, et al. 2018 [31] | Non-interventional study | Patients with a recommendation for treatment with GeloMyrtol or Sinupret and with a diagnosis of acute rhinosinusitis based on EPOS guidelines | n = 117 with GeloMyrtol n = 111 with Sinupret (BNO 1016) | Overall, GeloMyrtol and Sinupret had comparable effectiveness. The study presents with methodological flaws. |