Skip to main content

International Journal of Phytomedicine and Phytotherapy

Table 5 Comparative studies of herbal products in acute rhinosinusitis

From: Evidence-based management of acute rhinosinusitis with herbal products

Study Study design Population Sample size Main findings
Tesche S, et al. 2008 [43] Double-blind randomized clinical trial Patients suspected of having acute rhinosinusitis n = 75 with 5-component herbal preparation
n = 75 with cineole
Primary outcome:
The change in symptom-sum score from baseline to Day 7 was higher in the cineole group (− 11.0 ± 3.3) than in the other group (− 8.0 ± 3.0) (p < 0.0001).
Secondary outcome:
Changes in individual components of symptom-sum score were higher in the cineole group than in the other group.
Gottschlich S, et al. 2018 [31] Non-interventional study Patients with a recommendation for treatment with GeloMyrtol or Sinupret and with a diagnosis of acute rhinosinusitis based on EPOS guidelines n = 117 with GeloMyrtol
n = 111 with Sinupret (BNO 1016)
Overall, GeloMyrtol and Sinupret had comparable effectiveness. The study presents with methodological flaws.
  1. EPOS European position paper on rhinosinusitis and nasal polyps