International Journal of Phytomedicine and Phytotherapy
Table 2 Predicted Absorption of seven Ligands
Caffeic acid | Catechin | Ellagic acid | Epicatechin | Gallic acid | Quercetin | Rutin | |
|---|---|---|---|---|---|---|---|
Blood-Brain Barrier | BBB- | BBB- | BBB+ | BBB- | BBB- | BBB- | BBB- |
Human Intestinal Absorption | HIA+ | HIA+ | HIA+ | HIA+ | HIA+ | HIA+ | HIA+ |
Caco-2 Permeability | Caco2+ | Caco2- | Caco2- | Caco2- | Caco2- | Caco2- | Caco2- |
P-glycoprotein Substrate | Non-substrate | Substrate | Substrate | Substrate | Non-substrate | Substrate | Substrate |
P-glycoprotein Inhibitor | Non-inhibitor | Non-inhibitor | Non-inhibitor | Non-inhibitor | Non-inhibitor | Non-inhibitor | Non-inhibitor |
Renal Organic Cation Transporter | Non-inhibitor | Non-inhibitor | Non-inhibitor | Non-inhibitor | Non-inhibitor | Non-inhibitor | Non-inhibitor |